Companies by HQ LocationTech Companies and Startups Headquartered in San Francisco

Ouroboros Medicines is a biotechnology company that specializes in immunology and focuses on treating long-term immune-mediated illnesses. The company addresses chronic immune-mediated conditions directly by integrating scientific knowledge, a proven history of progressing cell-depleting treatments through clinical trials, and a strong pipeline.

MaxAI is a software platform that provides AI for fixing grammar and language translation services.

Tenvie Therapeutics is a biotechnology company founded to improve patients' lives with neurological, cardiometabolic, and ophthalmic diseases. The company is focused on developing small molecules targeting brain inflammation, metabolic dysfunction, and lysosomal issues, with a robust pipeline inherited from Denali Therapeutics. Tenvie is progressing a range of therapeutics aimed at addressing neurological, cardiometabolic, and ophthalmic conditions. Its collection of fully owned, highly brain-penetrant, and precisely designed peripherally restricted small molecules targets three main factors of disease: alleviating inflammation, correcting metabolic dysfunction, and rejuvenating lysosomal function.

Promptfoo finds & fixes LLM vulnerabilities before they are shipped to production. Its founders launched and scaled AI at Discord to 200M users using new research techniques specific to AI vulnerabilities and red-teaming. Promptfoo is open-source and is the most widely adopted tool in this space, with over 25,000 users at companies like Shopify, Amazon, and Anthropic.

I-Impact delivers reporting, analytics, performance management, and forecasting solutions.

Myriad AI provides a reliable and controllable AI-powered platform to put Compliance on Autopilot, enabling businesses to thrive.

nCompass Technologies is a platform for accelerating and hosting open-source and custom AI models. It offers low-latency AI deployment without rate-limiting. All with just one line of code.

Agree.com is the best solution for creating and managing contracts, streamlining negotiations, enhancing compliance, optimizing workflows, and converting more customers — all within one intuitive platform. View edits, track signatures, and get alerted on all upcoming key milestones. Include free, one-click e-signatures with identity verification on every agreement. Increase deal velocity and drive revenue impact with integrated payments.

Turgon empowers enterprises to streamline their entire business operations using AI. From enhancing supply chain and financial processes to managing customer relationships, Turgon enables businesses to deliver superior quality with faster turnaround times and reduced costs. Harness the power of Turgon to optimize your company's operations with AI. Reach out to us to if you want to "run" your company with AI.

Supermaven is an AI coding environment with several quality-of-life and technical enhancements.

AI-powered operating system for short-term rental hosts

Kiva AI - High Quality Scalable Output, Focused on the Human. Our mission at KIVA AI is to provide a comprehensive solution for all AI needs, focusing on data annotation, collection, curation, and fine-tuning. We prioritize delivering next-generation human feedback operations to enhance AI quality while reducing costs at scale. The market demand for sophisticated human feedback is increasing, particularly in data labeling, where supply falls short. Existing solutions often yield suboptimal results due to their lack of a human-centered approach, resulting in high costs, low scalability, and variable quality. KIVA AI addresses this challenge by prioritizing a human-centered approach. We hire the right people, empower them to do great work, and make sure incentives are aligned. Our approach reduces costs by over 45% while paying raters 50% more. Our target customers are organizations seeking to develop new AI models or enhance the performance of existing ones and are missing high quality human input. Our solutions aim to make development of AI applications scalable, accessible, high quality, and fast.

Generative Application Architecture and Platform for Developers.

Treeline is a software company currently based in San Francisco, California, United States. It has been founded in 2024.

Offcall is tackling for physician burnout by providing salary and work transparency, along with financial education.

Just words is a software company that makes it simple to create self-optimized content variations for emails and advertisements.

There’s huge potential in the new chapter of AI-powered customer service. But it will only be captured by companies that can shake up the industry models that hold back innovation. We’re a group of founders who have worked in customer experience for years. Our tech and our people have served billions of customers and provided exceptional service across the world. Crescendo is our vision for finally changing what’s held us back before. We’re combining the most advanced AI technology with the best human agents to provide a blended experience. We’re eliminating the separation between the contact center and the technology provider. With everything orchestrated together, we can dramatically accelerate improvements to agent and customer experience. That means customer service that’s more in sync, easier to manage, and more tightly integrated than ever before. And our customers will only pay for positive outcomes. It’s a brilliant harmony of AI and CX.

Nucs AI is a cutting-edge solution revolutionizing the clinical management of prostate cancer. The platform harnesses the power of artificial intelligence to offer unparalleled insights into tumor lesions, empowering both patients and healthcare professionals with advanced analyses and evidence-based decision-making tools. With Nucs AI, patients with prostate cancer can navigate their treatment journey with confidence, knowing they have access to the most comprehensive and personalized information available. It provides detailed assessments of tumor lesions, enabling healthcare professionals to tailor treatment plans to each individual's unique needs. By combining state-of-the-art AI technology with a commitment to patient care, Nucs AI is leading the way in transforming prostate cancer management.

BackOps is shaping the future of supply chain intelligence through advanced AI. Our solutions allow logistic teams to work at peak efficiency and focus on the things that matter most to your organization.

Ply Health’s platform delivers a better and faster contracting and credentialing experience. Using our tech + automation and behavioral health expertise, we've been able to get providers in network with payers weeks to months faster than other vendors. Ply Health partners with physical practices, digital practices, build-your-own-business platforms and new provider entrepreneurs in behavioral to magically simplify data collection, enrollment submission, follow ups and record keeping. Ply Health is backed by YCombinator and is based in San Francisco.

Prime Intellect democratizes AI development at scale. Our platform makes it easy to find global compute resources and train state-of-the-art models through distributed training across clusters. Collectively own the resulting open AI innovations, from language models to scientific breakthroughs.

Vue Protocol is an IT company that provides a decentralized social layer with restaking, security, and Web3 social.

Figure Markets is a company that uses blockchain technology to construct the future of private capital markets.

Flywheel Dynamix is a cloud meta-marketplace transforming how enterprises buy and sell cloud software with unmatched trust, visibility, and efficiency.

Who needs Lodge Compliance Hosts First-time and existing hosts must be aware of compliance regulations and recent laws that impact their business.Hotels Hoteliers need to be aware of short-term rental laws, as these regulations can impact their business.Property Managers Managing regulations for properties across different jurisdictions can be challenging. OTAs and Marketplace Stay informed about evolving compliance regulations and legislation that impact the online marketplace.

Fermah can generate proofs for any instance in which ZK is used. Fermah is credibly neutral and architected to support all proof systems. This includes zkVMs, zkEVMs, Groth16, and all other proof systems. It is optimized for cheap, fast, and reliable ZK proof generation.

WaveForms AI is a firm focused on developing improved audio intelligence through research and solutions. Its audio Language Models improve human-AI interactions by making them more realistic, engaging, and immersive. WaveForms AI aims to solve the Speech Turing Test by facilitating real-time speech discussions that inspire and connect.

Nubila is a pioneer in the Environmental, Social, and Governance (ESG) data industry, committed to revolutionizing sustainability projects with new solutions. Nubila uses AI and ESG tokenization to enhance decision-making, drive sustainable development, and generate financial solutions by creating the DePIN ecosystem's largest ESG Data Oracle.

Tenor is the AI for leadership. We're on a mission to make every manager more effective, at the world's largest companies.

Canvas AI is an AI based Software Development firm that offers Copilot for Customer Success.

Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease. The company seeks to rethink the drug discovery and development process from end-to-end by bringing together leading talent across three core areas: machine learning research to better understand biology, expansive data generation to power new models, and robust therapeutic product development to treat disease. Xaira is headquartered in the San Francisco Bay Area.

Viva Health provides AI automation and optimization platform for dental office operations. Our software includes an AI Receptionist for handling both inbound and outbound communications including calls, SMS, and emails. The platform also features Practice Optimization tools that analyze practice data to enhance scheduling and staff performance and Patient Insight tools that deliver in-depth analyses of patient behaviors and treatment patterns. Additionally, it includes a Comprehensive Communication Suite that centralizes all patient communications in one system. Designed to streamline administrative tasks and improve the efficiency of dental practices, Viva Health’s solutions help dental offices reduce overhead and improve the quality of patient care.

Crestal offers a decentralized platform that meets the objectives of Web3 applications through modular service architecture. The Crestal blockchain monitors and scores services using a Proof of Performance (PoP) consensus process.

Arini is an AI receptionist for dental practices that answers phone calls, and schedules appointments.

Taiki is an API that automatically pulls tax documents and data from payroll and financial institutions using AI.

EdgeTrace makes video data easily available and actionable for important businesses.

Blume Benefits is an insurance broker management platform that converts complex insurance quotes into clear and concise formats.

We automate, optimize, and enhance various operational processes. This includes tasks such as document processing, fraud detection, customer support, risk assessment, compliance monitoring, and transaction management. By integrating AI into these workflows, institutions can reduce manual effort, increase processing speed, and improve accuracy, resulting in more efficient operations and better customer experiences.

Piramidal offers artificial intelligence software that transforms brain activity into easy-to-understand health data to help diagnose neurological diseases.

OpenFunnel provides AI agents that help Go-To-Market teams find potential customers by detecting real-time intent signals from the internet.

Airfront automates the manual tasks directly from the inbox by using artificial intelligence.

Reviva builds all-in-one vertical software and AI for wellness businesses

Third Dimension's focus on immersive quality suggests they prioritize creating engaging and realistic experiences, which can be particularly beneficial for fields like gaming, virtual reality, architecture, and simulation training.

Across AI develops web app and chatbot that connects to various parts of the enterprise stack.

Chai Discovery creates Chai-1, a multi-modal foundation model designed for predicting molecular structures relevant to drug discovery. The model facilitates the unified prediction of proteins, small molecules, and nucleic acids, and is available for free for commercial applications. By enabling accurate predictions without the need for multiple sequence alignments, Chai-1 advances the capabilities of molecular modeling in the life sciences.

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Stand is a non for profit wild life conservation organization.

Cradle is a cryonics company that develops and proves the feasibility of human organs and whole-body reversible cryopreservation. That aims to focus on pausing and restarting biological functions through freezing to prevent tissue damage in dead bodies.

Spark Space enables the next generation of creators through artificial intelligence.

Viva is a transformative Gen AI solution for dental practices co-founded by experienced leaders in dental software and AI with successful exit. Our AI-driven platform offers seamless integration with practice management systems and other data sources in dental offices, handling tasks from administrative to communication, boosting efficiency, and reducing costs. By automating these processes, we increase service reliability and accuracy, offering a unique value proposition in the dental industry

Echo Chunk builds epic strategy games that generate themselves.

Revyl is an AI-enabled QA platform that allows teams to create, run, and maintain fully functional, automated E2E tests easily with no maintenance.

Yondu is a robotics engineering firm offering AI models for diverse robotic applications, including a voice-controlled drone.

Lift Labs is a creator of a suite of home health hardware for people living with Parkinson's Disease and Essential Tremor. Its core R&D focuses on areas of healthcare, sustainability, safety, and education. The company was founded in 2010 and is headquartered in San Francisco, California.

Thorntale is the first presentation program developed for data storytelling.

/dev/agents platform will work on new UI patterns that make it easier to build AI agents in a new cloud-based operating system.

Deterrence is a defense technology company focused on automating the production of reliable, safe energetics at scale.

c/side is a cybersecurity company that provides monitoring solutions, optimizing, and safeguarding vulnerable browser-side third-party scripts.

Corefin is an open-source lending platform that enables technology businesses to create and market lending solutions.

T-robotics is creating software that utilizes the inference power of the Visual-Language-Haptics models to detect tasks and combines it with the task execution power of robotic skills. In simpler terms, we create a box that attaches to any robot and makes it so smart that you only need to talk/write to it about what the robot should do.

Aidy is an AI assistant that helps to find, qualify, and apply for U.S. federal grants. It can quickly check the project's eligibility and competitiveness across various grant programs, and assist in filling out forms and drafting documents with AI.

EdgeRunner AI is a software company currently based in San Francisco, California, United States. It has been founded in 2024.

Pretzel AI is a cutting-edge, open-source substitute for Jupyter Notebook designed for data scientists and analysts that solves a number of persistent problems with Jupyter. It emphasizes AI, fosters collaboration, provides a contemporary development environment, and is fully open-source.

Practice your pitch any time you'd like with AI-powered prospects. Every call counts. Stop burning leads with half-baked talk tracks. Master the phone with real personas and scenarios.

Arva AI (LinkedIn) makes onboarding onto a bank/fintech as a business 100x faster and significantly cheaper. We've built a highly compliant AI agent that instantly handles all low/medium risk manual KYB work in real-time as a customer is onboarding, cutting reviews to seconds and ops spend by 80%.

Browserbase is a comprehensive platform for developers to host, administer, and monitor headless browsers in the cloud.

Zeko Labs is a zero-knowledge cross-chain scaling protocol built on Mina and designed for developers shaping the future of finance, AI, gaming, and the internet.

Oma Care is to empower, assist, and compensate people who care for our most vulnerable citizens—family caregivers.

Alacrity is a company that assists businesses in preventing ATOs (account takeovers) by offering a range of multi-factor authentication tools that provide both security and a positive user experience.

Reken is an AI & cybersecurity firm building a new type of AI platform and products to protect against generative AI-enabled threats, including deepfake social engineering and automated fraud. The company was founded in 2024 and is based in San Francisco, California.

Accelerate the adoption of electric vehicles, delivering data solutions that ensure every journey is powered by trust, reliability and sustainability.

Neeve is a cloud PaaS company transforming smart buildings and spaces and providing cybersecurity, secure remote, and cloud access.

Ark Labs is scaling Bitcoin with Ark, a new layer two protocol for fast, low-cost, seamless payments.

Kivu Bioscience is a biotech company developing next-generation antibody-drug conjugates to deliver best-in-class therapeutics and focused on rapidly advancing next generation transformative assets.

Open-source framework to accelerate development tasks with AI

Goodfire's mission is to advance humanity's understanding of AI by examining the inner workings of advanced AI models (or “AI Interpretability”). As an applied research lab, Goodfire bridges the gap between theoretical science and practical applications of interpretability.

Infactory is a software company currently based in San Francisco, California, United States. It has been founded in 2024 by Felipe Abello, Ken Kocienda, and Brooke Hartley Moy.

Endo Health creates a gamified ''AI endocrinologist'' for type 2 diabetes management. They are creating a pleasant AI medical assistant that will walk patients through every stage of diabetic control, complete with gamified involvement.

Trendies is a provider of the Base Ecosystem Token Launch Platform, which is primarily designed for token holders.

Ready to ditch the note-taking grind and focus on what matters most? Mili is your AI sidekick for streamlined workflows and personalized client experiences.

PathPilot offers an AI-powered platform that analyzes session replays to reveal user insights, UI issues, and improvement recommendations.

Nubila is a visual data mining and machine learning platform that is intended to be used by everyone (computer scientists, engineers, developers, and business domain experts) without a single line of code. It easily solves complex analytical problems by automating the lifecycle of predictive applications and allowing users to choose and compare multiply supervised and unsupervised machine learning algorithms that solve clustering, classification, and optimization problems. In addition, users can run state-of-the-art deep neural networks on an optimized analytics engine that is intended for big data processing. With this platform, users can explore multiple approaches quickly to spot trends and find the optimal solution.

Created by Humans enables creators to sell licensing rights for AI training and be reimbursed by AI firms.

Brain Jar Games is a new worldwide studio comprised of AAA professionals dedicated to creating bold and bright games that players want to share.

Leaping autonomously into the code is a recipe for bugs and errors. Instead, trust the tested code fixes for a reliable and successful solution.

GoldenBasis is a B2B fintech company that aims to help self-clearing firms receive account transfers with AI.

Experience the edge with Edgee’s Data Collection service. Harness powerful analytics solutions directly at the network’s edge to capture and analyze every user interaction as it happens. Whether you Google Analytics, Amplitude or any other analytics tool, and even if it’s your own first party analytics solution. Our edge-driven approach ensures not only speed but full compliance with data protection laws, giving you the power to make informed decisions without delay. Complete Data Visibility: Secure a 360-degree view of user interactions with no data loss, ensuring comprehensive insights. Unwavering Legal Compliance: Seamlessly meet global data privacy standards, upholding user trust and legal integrity Insights: Access real-time analytics to rapidly respond to user needs and market changes.

Grove's AI-accelerated PRM enables clinical research organizations to recruit and engage with participants at scale.

Hamming AI is an experimentation platform that helps teams build reliable AI products.

Pivotal AI is a software company currently based in San Francisco, California, United States. It has been founded in 2023 by Dipendra Jain.

Salient is an AI-powered sales platform that maximizes outbound engagement by sending outreach emails.

Boost Your Ad Performance with the Power of AdsGency.AI

Givefront is the financial operating system for non-profits.

MyShell is a decentralized and comprehensive platform for discovering, creating, and staking AI-native apps.

Veritas Labs is a SaaS company building AI agents for healthcare.

0G Labs is a technology business that specializes in blockchain technology, emphasizing decentralization for a range of industries and societal issues.

UnshETH is a cutting-edge DeFi protocol that promotes validator decentralization and provides the finest Ethereum staking experience for millions of users.

A powerful platform for companies to supercharge sales, customer success & operations on WhatsApp - manage WhatsApp groups & chats across multiple numbers, schedule bulk messages, create tickets, automate actions and more.

Codegen is a SAAS and artificial intelligence company that offers AI-assisted code development services.

Not Diamond focuses on optimizing the use of various AI models based on their strengths and capabilities.