San Diego has sunny weather, a large military presence, great Mexican food, plenty of breweries, fabulous beaches and a thriving tech scene. Most of the posts out there of "top tech companies in San Diego" don't do the sector justice so we're here to change that. Using data we at Employbl have harvested from the public web we're going to showcase one hundred and three tech companies and startups that are headquartered out of San Diego. This list won't show any companies that have satellite offices in San Diego, we're only looking at headquarters location. In the list we'll have the company name with a link to view more about them, the founded year, the latest funding investment round, total investment amount and a short description about the company. There are about 40 more companies in our database that are headquartered in San Diego but we've determined they haven't raised Venture Capital and the list is pretty long already so we decided not to include them. You can find the full list of San Diego tech companies by logging in and navigating to the companies search. To learn more about an individual company click on their profile to see jobs the company is hiring for, Venture Capital and Private Equity firms that have invested in the business, historical funding rounds and information about the founders.
Without further ado here's the list of San Diego tech companies and startups, sorted by the total amount of money each company has raised from investors. We're including publicly traded companies on this list.
| Company Name | HQ City | Year Founded | Latest Investment Round | Total Investment Amount | Company Description |
|---|---|---|---|---|---|
| Mirati Therapeutics | San Diego | 2013 | Post Ipo Equity | $2,005,600,000 | Targeting the genetic and immunological drivers of cancer. |
| Fate Therapeutics | San Diego | 2007 | Post Ipo Equity | $1,212,228,352 | Guiding Cells to Improve Lives |
| Maravai LifeSciences | San Diego | 2014 | Post Ipo Equity | $1,000,000,000 | Enabling the miracles of science. |
| Cue Health | San Diego | 2010 | Private Equity | $899,603,328 | Cue Health is a health technology company that develops professional and consumer connected medical diagnostics. |
| ACADIA Pharmaceuticals | San Diego | 1993 | Post Ipo Equity | $811,734,976 | Acadia is trailblazing breakthroughs in neuroscience to elevate life. |
| Kura Oncology | San Diego | 2014 | Post Ipo Equity | $791,425,472 | Kura Oncology, Inc. operates as a clinical stage biopharmaceutical company. The Company focuses on discovery and development of personalized therapeutics for the treatment of tumors and blood cancers. Kura Oncology offers development programs for cancers with high unmet need, including lung, colorectal, thyroid, blood, and pancreatic cancers. |
| Gossamer Bio | San Diego | 2015 | Post Ipo Equity | $600,000,000 | Gossamer Bio is a San Diego-based company focused on the discovery and development of novel and differentiated therapeutic products, to address high unmet needs amongst various targeted patient populations. Founded by the former Receptos executive team, Gossamer Bio’s strategy will be to leverage an asset-rich in-licensing environment, with a focus on areas of high unmet need, utilizing a team with a strong track record of execution in immunology, inflammation, fibrosis and oncology. |
| ClickUp | San Diego | 2016 | Series C | $537,500,032 | A fundamentally new way to work. |
| Shield AI | San Diego | 2015 | Series E | $513,144,992 | Shield AI, Inc. operates as an artificial intelligence robotics company. The Company protects service members and innocent civilians with artificially intelligent systems which enables robots to see, reason about, and search the world. Shield AI serves customers worldwide. |
| Evofem Biosciences | San Diego | 2009 | Post Ipo Equity | $470,800,000 | Developing and commercializing products that address unmet needs in women’s sexual and reproductive health. |
| Element Biosciences | San Diego | 2017 | Series C | $401,000,000 | Element Biosciences is a multi-disciplinary startup focused on innovating genetic analysis tools for the research and diagnostic markets. The Company's technology broadens the end-user experience through improved data quality and simplified workflows to benefit discoveries and diagnosis in healthcare. |
| Arcturus Therapeutics | San Diego | 2013 | Post Ipo Equity | $302,380,064 | Clinical-stage messenger RNA medicines company |
| Erasca | San Diego | 2018 | Series B | $300,000,000 | Our mission at Erasca is embedded in our name: To erase cancer. |
| Wiliot | San Diego | 2017 | Series C | $269,000,000 | Wiliot Inc. designs and manufactures semiconductors. The Company offers semiconductors for moisture sensing, step counting, inventory control, navigation, wiring replacement, access cards, and consumer electronics. Wiliot serves customers worldwide. |
| Sorrento Therapeutics | San Diego | 2006 | Post Ipo Equity | $264,418,496 | Sorrento Therapeutics, Inc. is a biopharmaceutical company. The Company researches human therapeutic antibodies for the treatment of cancer, inflammation, metabolic, and infectious diseases. |
| Tealium | San Diego | 2008 | Series G | $263,900,000 | Tealium is a US headquartered American company founded in 2008 in San Diego, California that sells enterprise tag management, an API hub, a customer data platform with machine learning, and data management products. |
| BioAtla | San Diego | 2007 | Post Ipo Equity | $261,500,000 | BioAtla LLC is a biological service company. The Company specializes in next generation protein and antibody engineering for the pharmaceutical industry. BioAtla is an organization with operations in both the US and China. |
| RayzeBio | San Diego | 2020 | Series C | $258,000,000 | Targeted innovative radiopharmaceuticals for cancer |
| Cloudbeds | San Diego | 2012 | Series D | $248,440,000 | More Reservations. Happier Guests. |
| Applied Data Finance | San Diego | 2014 | Series Unknown | $239,300,000 | Applied Data Finance, LLC operates as a financial services firm. The Company offers loans and financing solutions to consumers. Applied Data Finance serves customers worldwide. |
| Neurelis | San Diego | 2007 | Series D | $206,081,952 | Neurelis Inc., is a pharmaceutical company. The Company develops and commercializes product candidates for the treatment of central nervous system disorders, acute epilepsy, and anxiety episodes. |
| Platform Science | San Diego | 2015 | Series C | $197,700,000 | Making it easy for enterprise trucking fleets to develop, deploy, and manage mobile devices and applications. |
| NetraDyne | San Diego | 2015 | Series C | $197,520,544 | The Power of Vision: Transforming Road Safety. Every Second of Every Day. |
| Kandji | San Diego | 2018 | Series C | $188,375,008 | Next-generation Apple device management for macOS, iOS, iPadOS, and tvOS. |
| Plexium | San Diego | 2017 | Series B | $165,000,000 | Plexium is a drug development startup that leverages techniques from various physical science and computational disciplines. The company develops ‘molecular glues’ that alter E3-ligase substrate recognition; inducing, inhibiting, or modulating degradation of proteins for therapeutic benefit. It utilizes DNA-encoded libraries to search for molecular-glue degraders in high throughput cell-based assays. Plexium was founded in 2017 and is based in San Diego, California. |
| Brain Corp | San Diego | 2009 | Series D | $161,000,000 | Brain Co.,Ltd. was founded in 1973. The company's line of business includes providing computer programming services. |
| Wildcat Discovery Technologies | San Diego | 2006 | Series D | $160,000,000 | Wildcat Discovery Technologies Inc. provides research and development services. The Company focuses on the discovery of advanced materials for clean energy technology applications. Wildcat Discovery Technologies serves the alternative energy sector in the United States. |
| Locana | San Diego | 2016 | Series B | $155,550,000 | Creating RNA-targeting gene therapies to treat devastating diseases |
| Genalyte | San Diego | 2007 | Series Unknown | $141,800,000 | Move data. Not blood. |
| Avidity Biosciences | San Diego | 2013 | Series C | $140,067,856 | At Avidity, we are developing a new class of oligonucleotide-based therapies. |
| Truvian Sciences | San Diego | 2015 | Series C | $134,100,000 | Truvian disrupts the blood-testing industry by developing an automated, benchtop diagnostic system to provide lab-accurate results. The blood-testing system combines chemistry, immunoassays, and hematology assays in one device. With its 20-minute, single-run wellness panel that requires only several drops of blood, the company aims to cover about 40 commonly ordered diagnostic tests, including a lipid panel, metabolic panel, and complete blood cell count. |
| Drata | San Diego | 2020 | Series B | $128,240,856 | Drata is an advanced security and compliance automation platform with the mission to help companies earn and keep the trust of their users, customers, partners, and prospects. Drata helps companies streamline their SOC 2 compliance through continuous, automated control monitoring and evidence collection, resulting in lower costs and time spent preparing for annual audits. |
| Founders First Capital Partners | San Diego | 2015 | Series A | $120,000,000 | Helping companies grow and scale through strategic advisory and revenue-based investment. |
| Escient Pharmaceuticals | San Diego | 2018 | Series B | $117,500,000 | Escient Pharmaceuticals, Inc. operates as a pharmaceutical company. The Company focuses on developing drugs for a wide range to address serious and unserved medical needs across a broad range of therapeutic indications. Escient Pharmaceuticals serves customers in the State of California. |
| Kneron | San Diego | 2015 | Series B | $115,000,000 | Kneron, Inc. provides artificial intelligence solutions. The Company desings and develops integrated software and hardware edge AI solutions for smart home and surveillance, phone, robot, drone, and IoT devices, as well as offers emotion and behavior recognition solutions. Kneron serves customers in the United States. |
| Neomorph | San Diego | 2020 | Series A | $109,000,000 | Advancing the science of targeted protein degradation to destroy ‘undruggable’ proteins and cure disease. |
| Insightful Science | San Diego | 2017 | Seed | $100,000,000 | Insightful Science is a software company with purpose-built data analysis and bioinformatics applications for life sciences. The company portfolio serves a diverse set of 1 million scientists in academic, corporate, and government institutions around the world. |
| Zebit | San Diego | 2015 | Debt Financing | $90,115,280 | Publicly Traded Company on ASX |
| BlueNalu | San Diego | 2017 | Convertible Note | $84,750,000 | Cellular aquaculture company, satisfying the global appetite for seafood in a fresh, sustainable & humane way. |
| Measurabl | San Diego | 2013 | Series C | $79,610,000 | Measurabl Inc. designs and develops software solutions. The Company specializes in sustainability reporting, benchmarking, CDP, GRI, and data import. Measurabl serves customers in the United States. |
| Cordial | San Diego | 2014 | Series C | $73,550,000 | Use real-time data to deliver personal, relevant, and emotionally intelligent messages. |
| BlossomHill Therapeutics | San Diego | 2020 | Series A | $71,000,000 | BlossomHill Therapeutics, Inc. is a small molecule drug discovery and development company focused on unmet medical needs in oncology and autoimmune disorders. |
| Alterome Therapeutics | San Diego | 2021 | Series A | $64,000,000 | Alterome Therapeutics is a precision oncology biotech developing alteration-specific therapeutics to address high value and validated oncogenic drivers. |
| Workiz Inc. | San Diego | 2015 | Series C | $60,250,000 | Founded in 2015, Workiz is a SaaS CRM platform for small to medium-sized on-demand field service businesses, such as locksmith, carpet cleaning and appliance repair. With Workiz, field service pros can grow their business by ditching antiquated business management methods such as pen and paper, Excel spreadsheets and Google Calendar. Workiz provides an easy-to-use platform which allows them to manage their scheduling, invoicing, payment processing, and more. |
| GoSite | San Diego | 2013 | Series B | $59,750,000 | Helping bring America's small businesses online |
| Concert Health | San Diego | 2016 | Series B | $56,500,000 | America’s leading behavioral health medical group with a turnkey solution for primary care |
| Ascus Biosciences | San Diego | 2015 | Series B | $51,000,000 | Ascus Biosciences develops computational and genomics-based technology platform to discover and develop next-generation microbial products. The company was founded in 2015 and is headquartered in San Diego, California. |
| XinThera | San Diego | 2021 | Series B | $50,000,000 | XinThera is a drug discovery company focused on building small molecule oncology and immunology pipeline. |
| Adcentrx Therapeutics | San Diego | 2021 | Series A | $50,000,000 | Adcentrx is a biotechnology company focused on accelerating breakthroughs in protein conjugate therapeutic development for cancer and other life-threatening diseases. By combining the targeting precision of biologics and the disease fighting power of small molecule payloads, Adcentrx strives to develop next generation targeted therapies for improving patient treatment options. |
| Legend3D | San Diego | 2001 | Series C | $47,801,704 | Legend 3D is an American independent stereoscopic Visual Effects Film production company Based in Los Angeles, California. |
| KnuEdge | San Diego | 2005 | Series Unknown | $47,000,000 | KnuEdge is building the world's most scalable compute fabric designed for machine intelligence. |
| Replicate Bioscience | San Diego | 2021 | Series A | $46,000,000 | Replicate Bioscience creates novel oncology treatments to prevent and reverse drug resistance through a self-replicating RNA platform called SynRGY. By deploying SynRGY technology, the company aims to design novel treatments that prevent the occurrence of drug resistance and create solutions that enhance the effectiveness of many immuno-oncology regimens. |
| Mosaic.tech | San Diego | 2019 | Series B | $45,900,000 | Mosaic is a Strategic Finance Platform that transforms the way business gets done |
| SkySafe | San Diego | 2015 | Series B | $45,000,000 | SkySafe is a developer of technology to disable and take over rogue consumer drones. |
| Biocept | San Diego | 1993 | Post Ipo Equity | $43,200,000 | When treating cancer, it's no longer an either/or world. It's all about the AND. |
| AristaMD | San Diego | 2013 | Series B | $36,875,000 | Transforming Primary Care • Improving Patient Outcomes |
| Ocelot Bio | San Diego | 2020 | Series A | $36,000,000 | Ocelot Bio brings new treatment options to patients with severe liver disease. The company was founded in 2020 and is headquartered in San Diego, California. |
| Accel Robotics | San Diego | 2015 | Series A | $35,519,000 | Accel Robotics develops a 360-degree visual intelligence platform intended to improve customer experiences. Its camera-based AI system allows any shopper to enter a store, pick the items they want, then walk out, receiving a receipt via text or app notification, allowing businesses to run their stores with ease and confidence and enabling customers to have a checkout-free and more convenient shopping experience. |
| Graviton | San Diego | 2020 | Series D | $35,000,000 | Graviton develops novel therapeutics for the treatment of autoimmune, cancer, certain genetic, fibrotic, and other serious diseases. TDI01, a highly selective, potent inhibitor of Rho/Rho-associated coiled-coil containing protein kinase 2 (ROCK2) is currently being studied in the United States for the treatment of idiopathic pulmonary fibrosis (IPF). Graviton anticipates entering human clinical studies in the U.S. in 2021. |
| Mercato | San Diego | 2015 | Series A | $34,700,000 | Order your groceries from the best local markets and have them delivered straight to your door within hours. |
| Trovata | San Diego | 2016 | Series A | $30,550,000 | Automated Cash Management & Forecasting, powered by Open Banking. |
| SupplyPro Inc | San Diego | 1995 | Series Unknown | $30,499,984 | Track and control the boring stuff that makes the cool stuff; manage who, what, where, when, how much and for what. |
| CourseKey | San Diego | 2015 | Debt Financing | $27,550,000 | Course Key, Inc. develops education software. The Company offers a platform that provides attendance, auto-graded assessments, interactive textbooks, engaging social channels, and analytics solutions. Course Key serves customers in the State of California. |
| Revelation Biosciences | San Diego | 2020 | Post Ipo Equity | $27,261,290 | Revelation Biosciences develops immunologic therapeutics and diagnostics designed to make the world a healthier place. |
| Turquoise Health | San Diego | 2020 | Series A | $25,300,000 | Turquoise Health is a health care company that simplifies administration to reduce the expense and complexity of healthcare. The company was founded in 2020 and is headquartered in San Diego, California, United States. |
| Codex | San Diego | 2013 | Series A | $25,000,000 | Codex DNA empowers researchers with the tools they need to rapidly and securely design, code, and create synthetic DNA. |
| Cardea Bio Inc. | San Diego | 2013 | Grant | $23,975,000 | Linking computers directly up with the live signals of biology. #LinkingUpToLife |
| Trust & Will | San Diego | 2017 | Series B | $23,030,000 | Trust & Will operates an online software tool to help people to create their own estate plans. The Company offers an online service providing legal forms and information. Trust & Will serves customers in the United States. |
| Totum | San Diego | 2018 | Series A | $22,000,000 | Revolutionary wireless technology for low-cost, global, indoor tracking and monitoring of billions of assets. |
| Vessel | San Diego | 2015 | Series A | $21,481,000 | Vessel is an at-home wellness tracker that helps in accessing, understanding, and optimizing health and wellness from the comfort of home. With Vessel, users can test 10 different health metrics in less than 10 minutes for around $10. Vessel works with some of the best doctors, nutritionists, and scientists to create its wellness cards and build food, supplement, and lifestyle recommendations tailored based on the results. |
| Blooma | San Diego | 2018 | Series A | $20,750,000 | Automated, AI-Driven Decision Support System (DSS) for Commercial Loan Origination |
| Daasity | San Diego | 2017 | Series A | $20,700,000 | Empowering direct-to-consumer brands to grow faster through data driven decision making. |
| HomeBay | San Diego | 2014 | Series A | $18,950,000 | Home Bay provides consumers a smarter way to sell homes with data-driven intelligence and on demand customer experience. |
| LeadCrunch | San Diego | 2013 | Series B | $18,180,000 | AI B2B Marketing |
| Surglogs | San Diego | 2015 | Series A | $17,500,000 | Surglogs streamlines and automates the administration of logbooks, medications, supplies, in-services, and drills in healthcare facilities. The outdated pen-and-paper method is replaced with a HIPAA compliant state of the art digital application, complemented with a desktop portal that serves as an administrative dashboard. Surglogs was founded in 2015 and headquartered in California, United States. |
| PetDesk | San Diego | 2013 | Series B | $15,625,000 | We extend pet lives by bringing value to pet care providers and pet parents through our software and #1 mobile app |
| XYO | San Diego | 2012 | Initial Coin Offering | $13,635,000 | The people-powered location network. Join us in connecting blockchain dApps to the real world. |
| Yembo | San Diego | 2016 | Series A | $12,945,163 | Bringing the power of artificial intelligence to the relocation industry |
| DotLab | San Diego | 2016 | Series A | $12,650,000 | Dedicated to advancing women’s health. |
| XiltriX North America | San Diego | 2018 | Series Unknown | $12,225,000 | XiltriX Protects Your Science and Helps You Sleep at Night. |
| SpineZone | San Diego | 2007 | Series A | $12,000,000 | An alternative approach to neck and back pain without the use of surgery or medications. |
| Zluri | San Diego | 2020 | Series A | $12,000,000 | Zluri is a comprehensive SaaS management platform for IT teams. It helps IT teams Discover, Manage, Secure, and Comply across multiple SaaS applications, all from a single dashboard. In short, Zluri puts the IT team back in control of their new SaaS-ified landscape. |
| ViaTouch Media | San Diego | 2014 | Seed | $10,000,000 | Changing the way consumers shop! |
| FutureProof Technologies | San Diego | 2019 | Series Unknown | $9,500,000 | FutureProof Technologies is a financial analytics software company specializing in physical climate risks. |
| Blue Sky ELearn | San Diego | 2002 | Debt Financing | $7,500,000 | Founded in San Diego, CA, Blue Sky eLearn provides a full range of learning technologies that include a proprietary learning management system and a complete set of virtual event services. We help organizations capture educational content from either live or virtual settings, then manage and deliver that content to a global audience through our learning platform. |
| GroupSolver | San Diego | 2014 | Series Unknown | $7,281,497 | GroupSolver, Inc. provides consumer research platform. The Company develops a research platform that could analyze and quantify open-ended questions to increase company and product profile and driving inbound traffic. GroupSolver serves csutomers in the State of California. |
| Hedgedesk | San Diego | 2018 | Pre Seed | $7,000,000 | Hedgedesk specializes in rehumanizing markets with artificial intelligence. It is driven to rehumanize markets by making global trade safer and more accessible to all people everywhere. The company is headquartered in San Diego, California. |
| Arima Genomics | San Diego | 2015 | Series B | $7,000,000 | Genome Sequence and Structure |
| Micronoma | San Diego | 2019 | Convertible Note | $6,500,000 | Saving patient lives with a minimally-invasive, cancer screening test. |
| Ubiq Security | San Diego | 2019 | Seed | $6,400,000 | Ubiq is a technology company that has simplified the complex and messy world of encryption through a set of APIs, that are simple enough for any developer to use, yet scalable and extensible enough to encrypt data effortlessly across diverse applications and programming languages, cloud environments, and storage types. |
| Sleep Data | San Diego | 1995 | Private Equity | $6,000,000 | Clinicians who pioneered home sleep testing founded Sleep Data in 1995. Today, we have a staff of over 50 trained professionals—including Board-registered polysomnographic technicians and respiratory therapists—who will provide your comprehensive sleep apnea care. You will be treated with efficiency and the same discretion you would expect from your primary physician. |
| Palamedrix | San Diego | 2020 | Seed | $6,000,000 | Palamedrix is the first company to leverage DNA nanotechnology for revolutionary advancements in life science and medicine. |
| Personal AI | San Diego | 2020 | Seed | $5,900,000 | Creation is limited to the memories that you remember. Consumption is limited to the memories you remember to act on. Our goal is to unlock the value captured in the forgotten memories for everyone. We unlock this by creating a Personal AI that is trained entirely on top of your own individual memory so it is authentic to you, your Personal AI is the new medium to create and consume. |
| Splitero | San Diego | 2021 | Seed | $5,800,000 | Splitero is to provide homeowners with better options to access home equity without new debt or additional monthly payments. |
| Lively Root | San Diego | 2020 | Seed | $5,100,000 | Farm fresh plants delivered to your doorstep! |
| Sampling Human | San Diego | 2016 | Seed | $3,700,000 | The mission of Sampling Human is to couple health related decisions to their effects at the single cell level. It is inspired by the founders’ academic and professional efforts to extend what is measurable and to derive what must be measured. |
| Pack Digital | San Diego | 2019 | Seed | $3,000,000 | Empower your brand with a modern front-end that provides the benefits of headless, without the risk. |
| Cloud Water Filters | San Diego | 2021 | Seed | $2,300,000 | Cloud is a water brand, building a network of lifelong customers around the single promise of toxin-free, nutrient-rich water. Their products are easy to use, technology-enabled, and deliver pure water peace of mind. |
| DockWorks | San Diego | 2021 | Seed | $1,750,000 | Were a seed-stage B2B SaaS startup, with over $1.8mm in funding from amazing SaaS investors. Our platform allows marine professionals to manage payments easily, simplify scheduling and dispatching, as well as provide technicians with the accurate and reliable data they need to service marine equipment in the field. |
| T-REX | San Diego | 2012 | Series Unknown | $1,680,000 | T-Rex Group, Inc. designs and develops software solutions. The Company offers financial services software technologies. T-Rex Group serves customers in the United States and Israel. |
| Inngest | San Diego | 2021 | Pre Seed | $1,500,000 | Inngest is an organization currently based in San Diego, California, United States. It has been founded in 2021 by Tina Zheng and Tony Holdstock-Brown. |
| Eva.guru | San Diego | 2020 | Pre Seed | $1,500,000 | Eva provides Advanced Amazon Analytics and Intelligent Repricing Platform to the Brands, Private Label Sellers, and Resellers. |
| MANSCAPED | San Diego | 2016 | Angel | $500,000 | Precision engineered grooming tools and formulas. |
From this list it's clear there are some SaaS companies based in San Diego but the big emphasis seems to be on medical and biotech companies. Feel free to check out the full dataset via the company search functionality or check out some of our other articles below!