Opine helps to automate the pre-sales efforts for enterprise software transaction by removing the hassle of managing POCs. | Durham | NC | 5 - 20 | 2024 | $2,000,000 |
Keebler Health is an AI-first risk adjustment platform for providers and payers that are at risk for Medicare & Medicaid lives. Through a custom-built, transformer AI model, Keebler Health quickly uncovers risk adjustment opportunities with minimal encounter data. | | | 10 - 20 | 2023 | $6,000,000 |
Folio is a financial operations platform tailored for the hospitality sector that simplifies complex back-office processes, enabling properties to gain a competitive edge. | | | 2 - 10 | 2023 | $14,000,000 |
Bionic Health provides preventative health services. Bionic Health designs an iterative journey that allows us to understand your unique needs and make the changes that will have the biggest impact over time. | Durham | NC | 10 - 50 | 2022 | $3,000,000 |
5Metis is a new pure-play discovery company for crop health. The company is the result of a union of Boragen and AgriMetis platforms, to combine boron-based small molecule discovery and synthetic biology for discovering new modes of action. | Durham | NC | 10 - 50 | 2021 | $15,500,000 |
Elo Life Systems is reimagining the future of food - focusing on ingredients that empower consumers to feel good about the food they eat every day. From unique plant-based sweeteners to saving crops like the banana from extinction, Elo harnesses the untapped potential of nature to make food tastier,... Read more | Durham | NC | 20 - 50 | 2021 | $56,492,770 |
IOTA Software is a provider of data visualization that connects people, assets, and manufacturing processes. The company's team has extensive experience in the industrial process manufacturing sector. | Durham | NC | 20 - 50 | 2021 | $16,899,854 |
Plantd is a producer of building materials designed for green and zero-carbon housing. To ensure that carbon absorbed in the field is locked away inside the walls and floors of new homes, the company's products are created using industrial hemp and renewable grass. This enables customers to ensure cost management, carbon removal, and optimal material performance. They are business owners and engineers who think that reinventing the present is the first step in creating a prosperous future. | Durham | NC | 10 - 50 | 2021 | $32,000,000 |
Reselute designs, develops, and validates the proof of concept for an orthopaedic spacer using innovative technologies, enabling doctors to accelerate treatment and improve patient care. They develop medical devices intended for the treatment of orthopaedic implant-related infections. | Durham | NC | 5 - 10 | 2021 | $5,022,721 |
Coprata Inc. is pursuing non-invasive physiological monitoring that easily, safely and discreetly tracks health with little or no change to daily routine. Coprata is developing a Smart Sampling Toilet, a breakthrough wastewater technology licensed from Duke University and developed by researchers sp... Read more | Durham | NC | 5 - 10 | 2021 | $1,950,000 |
1 in 25 adolescents and young adults will be diagnosed with schizophrenia, bipolar, and other related conditions every year. Flourish Health provides treatment programs for teens and young adults with serious mental health diagnoses by combining high-touch, in-person support with virtual therapeutic and psychiatric care, empowering our members to achieve effective and lasting outcome. | | | 20 - 50 | 2020 | $26,000,000 |
BotBuilt is a software company that develops robotic systems and artificial intelligence solutions to simplify home construction. | Durham | NC | 5 - 20 | 2020 | $12,525,000 |
Tune Therapeutics strives to develop paradigm-changing cell and gene therapies that leverage epigenetic programming for the treatment of devastating diseases. | Durham | NC | 50 - 200 | 2020 | $215,000,000 |
Akros Medical is a developer of innovative solutions for orthopedic surgeons. The company was founded in 2014 and is headquartered in Durham, NC | Durham | NC | 1 - 10 | 2020 | $1,060,000 |
Neurophos is here to deliver the computational power of the human brain to artificial intelligence, by leveraging the massive parallelism and higher efficiency of optical computing, but based on a metmaterials technology that allows the use of all three spatial dimensions for data storage and processing. | Durham | NC | 10 - 50 | 2020 | $128,100,797 |
Avalo is a plant biology company that harnesses interpretable machine learning, genomic discovery, and evolutionary theory to rapidly design new crops for the future of agriculture. Their process uses AI-assisted plant breeding, so all products are non-GMO and support the natural diversity of the world around us. The technological core of Avalo isa discovery engine that can identify the genetic underpinnings of complex traits with minimal training. In turn, these findings are leveraged into high-precision, low-cost simulations and forecasts. Even in understudied crops, Avalo can reduce the time that it takes to produce new crops by years and reduce the cost by an order of magnitude. | Durham | NC | 10 - 50 | 2020 | $14,900,000 |
Pluto Health develops consumer health technology applications designed to aggregate electronic health record data. The company's application finds, integrates, and automates insights from their medical records and data across different health systems, pharmacies, and labs and also reminds users about tasks such as paying healthcare bills, tracking medications, and sharing health data with providers, empowering patients with tools for better care. | Durham | NC | 20 - 50 | 2020 | $8,900,000 |
We leverage our patent-pending technology to produce nutritionally equivalent breastmilk from cultured human mammary cells. With Biomilq, families can achieve the recommended six months of exclusive breastfeeding while alleviating the climate impacts of bovine-based infant formula. | Durham | NC | 20 - 50 | 2020 | $24,500,000 |
Leveraging 3D technology to bring custom protective devices to athletes and competitors everywhere. | Durham | NC | 5 - 20 | 2019 | $2,135,201 |
Gradient Health aims to label the world’s medical imagery, one pathology at a time. | Durham | NC | 5 - 20 | 2018 | $5,700,000 |
Data Driven Bioscience Inc operates as a biotechnology company. The Company develops a tools for clinical labs to apply genomics for the diagnosis and treatment of cancers. Data Driven Bioscience serves patients in the United States. | Durham | NC | 2 - 10 | 2018 | $120,000 |
Higharc is the all-in-one web platform that simplifies, connects and improves each step of design, construction and sales for home building. | Durham | NC | 50 - 200 | 2018 | $175,000,000 |
Arpio protects your AWS environments from catastrophic downtime due to region failures, ransomware, human errors, and other disasters. | Durham | NC | 10 - 50 | 2018 | $10,375,000 |
At inSoma Bio they borrow nature’s own designs to develop unique products for reconstructive plastic surgery. Their product enables surgeons to use a person’s own tissue instead of synthetic implants and fillers to improve procedures like breast and facial reconstruction. | Durham | NC | 5 - 20 | 2018 | $7,274,313 |
Upstream Biotechnology develops broad-spectrum disease resistant crops using patented technologies to eliminate pesticide use, lower production costs, and boost agricultural yield. | | | 1 - 10 | 2018 | $625,000 |
SWIR Vision Systems Inc., a North Carolina based startup company launched from RTI International, is developing and commercializing a novel, breakthrough image sensor technology, delivering affordable, infrared imaging cameras with full HD resolution. The company's AcurosTM cameras provide high clar... Read more | Durham | NC | 20 - 50 | 2018 | $7,510,000 |
Luvaura develops methods and medical devices designed to treat veins. Luvaura's methods include positioning a distal end of a delivery tool, such as a syringe and needle or catheter, within the vein; introducing media from the delivery tool into the vein; and creating an occlusion in the vein by exposing the media to energy using an artificial energy source. | Durham | NC | 5 - 10 | 2018 | $27,072,526 |
Creator of BrewMonitor®, real-time fermentation monitoring for craft brewers. Track DO, pH, density, pressure, temp & conductivity from any phone, tablet or PC. | Durham | NC | 10 - 50 | 2017 | $52,576,274 |
Ten63 Therapeutics is a venture-backed startup developing durable therapeutics against some of the world’s most lethal diseases. | Durham | NC | 10 - 50 | 2017 | $15,900,000 |
biospatial is a platform that analyzes prehospital data to support the missions of public sector and commercial healthcare entities. biospatial partners with state and local Emergency Medical Services (EMS) agencies to aggregate and analyze prehospital data in the form of electronic Patient Care Reports. Using machine learning and artificial intelligence on this unique dataset, biospatial has developed platforms for healthcare entities to analyze prehospital data with the goal of improving patient outcomes across the US healthcare system. Founded in 2017, Biospatial is headquartered in Durham, North Carolina. | Durham | NC | 10 - 20 | 2017 | $7,524,742 |
Pairwise is a start-up food company that uses technology to break down the barriers that keep people from eating produce. They are passionate about reducing diet-based disease by driving an increase in the consumption of fruits and vegetables. | Durham | NC | 100 - 200 | 2017 | $155,000,000 |
CureMint empowers dental organizations with a cloud-based source-to-pay platform that manages their entire procurement lifecycle in one easy-to-use place. CureMint’s Procure module delivers a streamlined ordering experience that office staff will love while arming managers with the tools necessary to gain full control and visibility across their organization. CureMint’s Pay module removes the costly blindspots that exist between procurement and accounts payable departments by removing silos and streamlining invoicing and other A/P processes. | Durham | NC | 20 - 50 | 2017 | $4,150,000 |
restor3d, inc. provides surgical and medical instruments. The Company offers solutions which enables surgeons to improve the reconstruction and repair of the human body through 3D printed implants. restor3d operates in the State of North Carolina. | Durham | NC | 50 - 500 | 2017 | $395,715,622 |
IMMvention is developing therapies that inhibit multiple inflammasome pathways that result in increased cytokine production that is at the root cause of some of the following diseases. | Durham | NC | 5 - 20 | 2017 | $9,149,999 |
Leyline provides financing that bridges the gap between mid-stage development and construction. By investing in the pre-construction phase of renewable energy projects we accelerate the development process and help developers scale their business. Having developed, built and financed over 73 utility-scale renewable energy projects totaling more than 350MW we understand what it takes to make a project truly shovel-ready. | Durham | NC | 20 - 50 | 2016 | $360,000,000 |
Modern Energy is an energy asset management firm that invests in businesses that bring emerging energy technologies to market and the energy resources those businesses produce. From energy efficiency in the United States to solar projects in Brazil to virtual power plants in the United Kingdom, Modern supports leaders in the transition to a digital energy ecosystem. New hardware and software innovations are rapidly reshaping the competitive landscape of energy markets. Cost reductions in energy efficiency, generation, management, and storage are changing the economics of energy markets. At the same time, new software applications are dramatically reducing the transaction costs required to purchase, aggregate, dispatch, and monetize millions of small energy installations, ranging from industrial coolers to solar home systems. Together, these changes represent a once in a century transformation of their energy ecosystem and enable Modern Energy to play a catalytic role in bringing market-moving price and technology trends to scale. It was incorporated in 2010 and is based in Durham, North Carolina. | Durham | NC | 20 - 50 | 2016 | $178,875,008 |
Regrow is a multinational team of scientists, agronomists, engineers, and software developers committed to transforming the supply chain from farm to fork to ensure a prosperous future for people and the planet. We are in 8 countries, speaking 10 languages, and growing fast. Join us! | Durham | NH | 50 - 200 | 2016 | |
Altis Biosystems is a spin-out company from the University of North Carolina at Chapel Hill and based in Durham, North Carolina. The intellectual property behind its stem cell platform was created as part of an NIH Transformative Research Award to develop a microfluidic organ-on-a-chip mimic of the... Read more | Durham | NC | 20 - 50 | 2015 | $6,664,965 |
Sift Media is leveraging advanced AI and machine learning algorithms to hyper-target app install ads for its clients. | Durham | NC | 50 - 120 | 2015 | $4,690,000 |
WeaveUp, Inc. is a software startup that enables billion dollar companies to efficiently enter the textile print-on-demand market using groundbreaking color customization, workflow, and sales tools. The last time the textile market saw a change like this, hot air balloons were the latest technology. | Durham | NC | 10 - 20 | 2015 | |
ValueBase is a software provider that focuses on offering cutting-edge options for real estate assessment.ValueBase's mission is to provide the most complete and accurate data and tools possible to property appraisers and other professionals in order to aid them in making educated judgments. | Durham | NC | 5 - 20 | 2015 | $13,900,000 |
The Looma Project Inc provides software solutions. The Company develops a storytelling platform that offers story strategy consulting, AI driven story methodology, film maker network, post-campaign analysis and attributes, and pre-campaign predictive analytics solutions. Looma Project serves customers in the State of North Carolina. | Durham | NC | 20 - 100 | 2015 | $12,575,000 |
EnMass Energy is a digital procurement and operations platform for global waste-to-energy supply chains. | Durham | NC | 10 - 50 | 2015 | $2,153,485 |
WhiteSpace Health, Inc. provides data analytics and cloud healthcare intelligence solutions. The Company offers cloud based software solutions to improve practice engagement, reducing cost, and productivity. WhiteSpace Health serves health care sectors in the United States. | Durham | NC | 20 - 50 | 2014 | $18,000,000 |
Edison Agrosciences is an agricultural biotechnology company dedicated to developing and commercializing innovative solutions for the production of plant-based industrial materials, with a primary focus on the development of alternative rubber crops. They are engineering yield improvements and the novel production of industrial materials in suitable plant systems. Edison has an emerging IP portfolio covering multiple technical strategies and they are developing strategic partnerships to mitigate the risk of pilot scale crop and product validation. Edison’s strong leadership team has a track record of success in industry. | Durham | NC | 5 - 10 | 2013 | $1,675,000 |
Used by over 25% of the top brokerage firms and over 15% of the top mortgage originators in the U.S., Adwerx delivers personalized, omnichannel brand marketing and automation at enterprise scale. | Durham | NC | 50 - 100 | 2013 | $26,184,020 |
410 Medical is a medical device company dedicated to developing innovative products that enable frontline medical providers to improve care. | Durham | NC | 20 - 100 | 2013 | $64,249,993 |
ValueBase is a personalised business intelligence company specialising in healthcare. We believe that BI is a core driver of competitive advantage – so we’ve developed a range of personalised intelligence tools to help pharma companies achieve commercial excellence. VB tools combine human and artificial intelligence, providing unique data and analytics that informs evidence-based decision-making. Our data is used by many of the world’s leading biopharmas – including 7 of the top 10 global pharma companies – to power their market access and commercial strategies. The ValueBase portfolio marries digital technology with specialist healthcare expertise to turn disorganised data into actionable insight. We use algorithm-based methodology to capture large, complex volumes of open data. Our healthcare experts check, connect and contextualise it. And our digital interfaces bring it to life so our customers can interrogate it, understand it and, better still, act on it. Our flagship innovation is Formulytics – a digital analytics tool that tracks and evaluates UK medicines formularies. It helps pharmaceutical companies monitor formulary adoption, benchmark competitors and identify early adopters and local barriers. It provides real world, real-time and longitudinal insights. ValueBase is a member of the Open Data Institute. Our team has long-standing expertise in pharmaceutical marketing, market access, communications and data science. | | | 5 - 20 | 2012 | $13,900,000 |
Sovereign's Capital operates as a venture capital firm. The Company focuses on consumer products and services, healthcare, and information technology sectors. Sovereign's Capital has offices in the US and Indonesia. . | Durham | NC | 20 - 100 | 2012 | |
ServiceTrade helps commercial service companies deliver an amazing customer experience and increase the value of their business.
ServiceTrade is a software as a service platform that manages job scheduling, technician scheduling and efficient routing for single or multiple offices in an easy user interface. Documentation of the work performed is stored online and delivered to customers’ inboxes for always-on access to service history. Online communication and coordination between field technicians, the home office, and the customer make each appointment more professional.
In the book The Digital Wrap: Get out of the Truck and Go Online to Own Your Customers, ServiceTrade CEO Billy Marshall describes techniques for taking service activities online to strengthen customer relationships and maximize the value of your service contracting brand. Get the book at digitalwrapbook.com. | Durham | NC | 100 - 500 | 2012 | $119,811,784 |
A pioneer in the field of epigenetics and chromatin biology, EpiCypher is a bioscience company developing transformative technologies and delivering superior products to researchers worldwide. | Durham | NC | 20 - 100 | 2012 | $3,440,300 |
Bull City Venture Partners operates as a venture capital firm. The Company invests in software, health IT, mobile, internet, e-commerce, and digital media companies. Bull City Venture Partners operates in the United States. | Durham | NC | 10 - 50 | 2012 | |
Pattern Health is on a mission to accelerate digital health innovation. They partner with researchers, clinical innovators, and their institutions to develop and implement digital health programs, surveys, and clinical tools. They don’t stop there, though. They bridge the gap between research and real-world application by providing a pathway for digital health innovations to be adopted for clinical use. Programs are available for licensing by any healthcare institution, bringing innovators and healthcare providers together in a collaborative community that expands the impact of innovation. Their capabilities are enabled by a single digital health platform that makes it easy to deploy existing programs or for innovators to build novel solutions. Their configurable platform offers built-in security and compliance, software and device integrations, and digital health best practices. They offer fast and cost-effective program development through the combination of their platform and deep healthcare and behavioral science expertise. | Durham | NC | 10 - 20 | 2012 | $4,800,000 |
Archivesocial, Inc. was founded in 2011. The company's line of business includes designing, developing, and producing prepackaged computer software. | Durham | NC | 200 - 500 | 2011 | $56,195,970 |
CloudFactory is a global leader in combining people and technology to provide workforce solutions for machine learning and business process optimization. Our professionally managed and trained teams work with high accuracy using virtually any tool. We process millions of tasks a day for innovators including Microsoft, GoSpotCheck, Hummingbird Technologies, Ibotta, and Luminar.
We exist to create meaningful work for one million talented people in developing nations, so we can earn, learn, and serve our way to become leaders worth following. We’re on four continents, with offices in the U.K., U.S., Nepal, and Kenya. To learn more, visit www.cloudfactory.com. | Durham | NC | 10 - 1,000 | 2010 | $78,000,000 |
Cell Microsystems is an early growth stage company that develops, manufactures, and markets innovative products for single-cell biology. | Durham | NC | 20 - 50 | 2010 | $29,966,164 |
Kevel (previously Adzerk) is helping brands everywhere drive more online revenue through sponsored listings, internal promotions, native ads, and more. Their award-winning platform handles over three billion API requests each day, and it’s helped industry leaders like Yelp and Ticketmaster shorten t... Read more | Durham | NC | 50 - 200 | 2010 | $45,150,000 |
Validic is the healthcare industry’s premier technology platform for convenient, easy access to digital health data from best-in-class clinical and remote-monitoring devices, sensors, fitness equipment, wearables and patient wellness applications. | Durham | NC | 50 - 100 | 2010 | $30,358,500 |
FlexGen develops software and power electronics for energy storage products, reducing electricity costs, and improving performance and reliability for power consumers worldwide. It loves energy storage and working with the most innovative and promising battery and capacitor companies in the world, opening the door for their technologies to utility, consumer, and industrial power systems. It was founded in 2014 and is headquartered in Durham, North Carolina. | Durham | NC | 50 - 500 | 2009 | $357,500,000 |
NET Power produces power from natural gas at costs comparable to existing technologies. All CO2 is captured at no extra cost. | Durham | NC | 68 | 2009 | $690,000,000 |
Spreedly provides cloud-based PCI Level-1 infrastructure for payments software. Businesses use Spreedly to connect to multiple payment gateways, payment receivers, and a secure credit card vault – all through a single API. That enables their customers to do more business, in more markets, with more partners – all while minimizing PCI compliance scope. | Durham | NC | 50 - 200 | 2007 | $81,070,370 |
IDEA Fund Partners is a venture capital firm focusing on technology and business model innovations. | Durham | NC | 10 - 50 | 2006 | |
Windlift is an engineering and computer programming company that develops airborne wind energy systems. | Durham | NC | 10 - 20 | 2006 | $199,879 |
Precision BioSciences utilizes its proprietary ARCUS Genome Editing method to overcome cancers, cure genetic diseases, and enable development of safer food. | | | 68 | 2006 | $342,400,000 |
Teamworks is a communication and operations platform for athletic organizations. | Durham | NC | 100 - 500 | 2005 | $422,151,452 |
WORKSMART is a team of seasoned business professionals with experience in process-driven industries like manufacturing, healthcare, financial services and government.
WORKSMART consultants deliver industry specific counsel and integrated end-to-end solutions that support our clients strategic, operational, and financial goals. | Durham | NC | 20 - 200 | 2004 | |
Humacyte Global, Inc. operates as a regenerative medicine company. The Company develops and manufactures bioengineered human tissues and organs to treat various diseases and injuries, with a focus on vascular applications. Humacyte Global serves patients in the United States. | | | 184 | 2004 | $955,562,368 |
Hatteras Venture Advisors III, LLC operates as a venture capital firm. The Company invests in early stage companies with a focus on biopharmaceuticals, medical devices, diagnostics, health care information technology, and related opportunities in human medicine. Hatteras Venture Advisors III serves its clients in the United States. | Durham | NC | 20 - 50 | 2000 | |
Trosa is an addiction treatment center that provides residential recovery programs for men and women with substance use disorders. | Durham | CT | 50 - 100 | 1994 | $1,040,000 |
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