Senior Research Asscociate, Biology- Temporary - Alector

Job Title: Senior Research Asscociate, Biology- Temporary
Job Location: South San Francisco, CA
Job Listing URL: https://jobs.lever.co/alector/3d0c13b6-9c0f-4390-acd3-1622a28af1ad
Job Description: Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.

Alector is seeking a Senior Research Associate (SRA) in Biology to join our dynamic team. This SRA will be responsible for conducting in vitro studies and analytical assays to evaluate potential therapeutics for neurodegenerative diseases. This role will involve in vivo and in vitro sample processing for downstream biochemical assessments, assisting in cellular and animal studies, and maintaining accurate records to support PK/PD, efficacy, safety, POC, and MOA studies.
Core Job Responsibilties
Perform in vitro pharmacology studies in IPSC-derived cellular models (iNeurons, iMicroglia, co-and triple-culture systems)
Collect and process biological samples (cell lysates, media, rodent brain, and other organs) for downstream analysis.
Assist in the development and optimization of cellular disease models, including Alzheimer’s disease, POC, MOA models.
Maintain accurate records of experiments, protocols, and data in electronic lab notebooks (ELN).
Collaborate daily with cross-functional teams, including Biology, ADPE, and Preclinical groups.
We'd love to hear from you if:
BS/MS in Neuroscience, Immunology, Biology, or a related field with 2+ years of industry research experience.
Hands-on experience with cell culture techniques, IPSC and primary rodent neuronal cell models
Experience with immunoblotting, ELISA, MSD, ICC, FACs, IHC
Familiar with confocal microscopy, neurohistology techniques
Proficient in Word, Excel, PowerPoint, and GraphPad Prism.
Excellent organizational and communication skills.
Strong attention to detail.
Highly adaptable and capable of adjusting to shifting priorities.
Able to work in a fast-paced and highly collaborative environment.