Senior Automation Engineer (I, II, III)

Cellares is revolutionizing cell therapy manufacturing. Cellares is developing a one-of-a-kind solution, The Cell Shuttle, to overcome the challenges associated with manufacturing so these life-saving therapies are…

Location: South San Francisco, CA
Company size: 50–200
Posted: 3w ago
Via: Lever

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Job listing · Updated 06 OCT 2026

Senior Automation Engineer (I, II, III)

Cellares· South San Francisco, CAView company profile

Job title: Senior Automation Engineer (I, II, III)
Job location: South San Francisco, CA
Job listing URL: https://jobs.lever.co/cellares/6f2ad7e3-1f28-46c4-a4e8-a432924632a3
Job description: Position Summary

We are seeking an Automation Engineer to drive and support the development, platforming and day-to-day operation of automated QC workflows in our Cell Q system at our South San Francisco, CA site. This role is central to translating newly developed assays into scalable, automated workflows ahead of transfer and validation on Cell Q.

The successful candidate will work hands-on to develop and program liquid handling methods, write and maintain Biosero Green Button Go (GBG) code, and test these methods to confirm functionality and performance before they move into validation. Working closely with Analytical Development, Quality Control, Software, Manufacturing and IT, the Automation Engineer will contribute to development, user training, technical documentation and controlled management of automated test methods.

Candidates should enjoy working in a fast-paced, mission-driven environment and be comfortable owning assay automation from early-stage development through hand-off for validation.

Responsibilities

Design and develop automated liquid handling protocols to platform new assays onto the Cell Q system

Partner with Analytical Development (AD) to translate manually developed assays into automation-compatible methods

Write and maintain Biosero Green Button Go (GBG) code to implement and integrate automation solutions

Design and execute validation experiments to optimize assay and workflow parameters.

Conduct testing of newly developed automated methods to confirm functionality and performance ahead of formal validation

Troubleshoot and iterate on liquid handler methods and GBG scripts throughout development

Collaborate with QC, Manufacturing, IT, and Quality to support the transition of developed assays into validated production use

Document method development, coding logic, and testing outcomes to support downstream validation and transfer

Monitor and refine automated workflows based on development and testing feedback to improve reliability and performance

Requirements

Bachelor's or higher degree in Engineering, Computer Science, Biotechnology, or a related field

2+ years of experience developing and programming liquid handling automation methods. Experience on Tecan Fluent preferred.

Hands-on experience coding in Biosero's Green Button Go (GBG) software, or equivalent scheduling software experience

Proficiency in programming languages such as Python or C#

Experience working cross-functionally to platform manual assays onto automated systems

Familiarity with flow cytometry, genomic, and cell-based assays

Experience with laboratory analytical instruments and automated systems

Familiarity with GMP documentation and change control practices, or ability to quickly learn regulated documentation requirements

Strong technical writing skills and experience authoring SOPs, documentation, and training materials

Excellent problem-solving skills and ability to troubleshoot technical issues during method development

Strong communication skills to collaborate effectively with cross-functional teams

Attention to detail and ability to manage multiple development efforts simultaneously

Creative, self-motivated, eager to take on a wide variety of tasks and grow with the evolving technology

Self-awareness, integrity, authenticity, and a growth mindset