SECTION I · THE BRIEF
Brief #26055Updated 06 NOV 2026SAN DIEGO HQAshbySEQUOIA CAPITAL
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Research Scientist II/Senior Research Scientist, Medicinal Chemistry

Entos uses machine learning-technology for energy and force evaluations required for R&D labs. Its technology assists in analyzing quantum molecular simulation. The software uses mean-field-cost quantum calculations to…

Location
San Diego HQ
Company size
50–200
Posted
Today
Via
Ashby
Section II · Full ProfileFree with an account
  • 01Comp band & equity packageLocked
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Research Scientist II/Senior Research Scientist, Medicinal Chemistry

Entos· San Diego HQView company profile


Job title
Research Scientist II/Senior Research Scientist, Medicinal Chemistry
Job location
San Diego HQ
Job description

POSITION

We seek a motivated, detail-oriented, experienced and creative chemist to join our Discovery team at Iambic Therapeutics in San Diego, CA. The role will entail managing external research support, coordinating with the medicinal chemistry and HTE team to facilitate compound library campaigns, and drug discovery efforts. Candidate should be motivated to work in an intensely collaborative, multidisciplinary, team-based setting. This position will be based in our San Diego Headquarters.

KEY RESPONSIBILITIES

  • Manage a team of FTEs/FFS teams at external CROs to drive molecular discovery efforts aimed to deliver intermediates, final targets, and reference compounds.

  • Support proposal development, scope definition, purchase orders, change orders, resource and FTE planning, budgeting, and commercial alignment throughout the project lifecycle.

  • Develop and manage integrated project plans, timelines, milestones, priorities, resources, action items, and deliverables to ensure effective and on-time execution.

  • Identify delivery risks, assess potential impacts, escalate critical issues, and drive resolution to maintain project momentum

  • Act as a liaison between Iambic, CROs, and other external collaborators

  • Communicate project updates clearly and effectively to the broader team and key stakeholders

  • Work as a senior member of the Chemistry research group and foster a culture of scientific excellence, innovation, and teamwork

QUALIFICATIONS

  • Ph.D. in Organic Chemistry with 3+ years of Pharma/bio-tech drug discovery experience.

  • Strong foundation in modern organic synthetic methods as exemplified by peer-reviewed publication track record.

  • Ability to thrive in a fast-paced, highly collaborative, and dynamic research environment.

  • Strong written and verbal communication skills; able to clearly convey technical results to vendors, colleagues and cross-functional partners.

  • Prior expertise in CRO management; demonstrated examples of problem solving within tight timelines.

  • Experience in managing vendor relationships and performance, exemplified by eliminating obstacles to maximize the value of external workflows.

  • Highly organized and detail-oriented.

ABOUT IAMBIC THERAPEUTICS

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai.

MISSION & CORE VALUES

Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

PAY AND BENEFITS

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

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Entos headquarters

San Diego, CA

Company size

50–200 employees

Founded

2019

Total raised

$377,999,966

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Funding rounds