Companies by HQ LocationTech Companies and Startups Headquartered in South San Francisco

Reprompt is the control panel for production AI systems.

Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.

Shinobi Therapeutics focuses on creating hypoimmune CD8αβ iPS-T cells that work with the immune system to treat cancer and other diseases. The company utilizes advanced immune evasion technology to enhance the effectiveness and accessibility of cell therapies. Shinobi's innovative approach aims to reduce costs and improve patient outcomes through durable responses and redosing capabilities.

Velorum Therapeutics produces powerful cancer treatments that starve tumors.

Kardigan is a patient-driven heart health firm that is revolutionizing cardiovascular drug development to produce medicines that take patients from symptom management to functional cures.

Noetik is an AI-native biotechnology company. Noetik leverages in advanced machine learning methods to discover and develop cancer immunotherapies.

NewLimit specializes in treating age-related diseases to extend the human health span. It works on developing epigenetic reprogramming medicines to treat diseases with large unmet needs.

Resilient, modular, reconfigurable, no-integration-code automated material flow and storage system enabled by robotics and AI

Midjourney is an artificial intelligence-powered artwork generator. It explores new thought mediums and expands the human species' imaginative powers. It is a small self-funded team focused on design, human infrastructure, and artificial intelligence.

Esker is a precision medicines company looking to eliminate the “all-comers” approach that is seen with today’s treatments for people with autoimmune disease. Even with the innovation of the last decade, many patients continue to cycle through the approved therapies while continuing to look for the right therapy to alleviate the impact of their disease without life-impacting side effects. Esker leverages a precision analytics platform, powered by Foresite Labs, coupled with a team of experts with deep experience in precision medicine drug development and immunology, in order to create medicines that change the lives of people with autoimmune disease.

coinroll is a secure and compliant fintech platform designed for institutional investors which facilitates effortless-full-cycle digital investments and provides up-to-date insights on emerging investment opportunities. coinroll achieves this with intense customer focus, a constant eye on evolving technologies, and a wealth of technical and digital financial expertise. Funds Raised Pre-Seed (SAFE) Friends and Family $500k closed March 2022

Deep Origin is a biotechnology company that offers a platform for life sciences R&D.

Wispr AI is a developer of the next-generation of neural interfaces to provide seamless interface with immersive technology. The company is working with the leading neuroscientist, hardware engineers, machine learning researchers, and product engineers to bring frontier technology to the mass consumer market. Wispr AI was founded in 2021 and headquartered in San Francisco, California.

FORMA is an incubator, accelerator, and curator of next-generation beauty brands launching as a multi-category platform. The company celebrates, supports, and seeks those changing the world through creative expression. Each brand in its portfolio is thoughtfully selected, acquired, or created because of the products it offers, the stories it tells, and the beauty it spreads. United by a shared call to create, Forma partners with inspiring founders to provide the resources, processes, and know-how to amplify their stories.

Atomic AI is a well-funded, early-stage biotech company transforming the rational design of molecules and medicines through the cutting-edge fusion of artificial intelligence and structural biology.

Sonoma Biotherapeutics is a company invloved the development of adoptive Treg therapies cell for autoimmune and degenerative diseases. Using next generation genome editing and target-specific cell therapy, Sonoma is focused on developing its best-in-class platform across the entire spectrum of Treg cell therapeutic capabilities. Founded by pioneers in Treg biology and cell therapy, the company brings together leading expertise and proprietary methodologies for the discovery and development of disease modifying and curative therapies.

Interline Therapeutics is a drug discovery platform that enables the company to map and correct dysfunctional protein communities. It uses genomics, proteomics, structural biology, and computational chemistry to map and modulate protein communities. Interline leverages recent advancements in these technologies, as well as collaborations with leading academic groups, to develop a precision medicine platform focused on three essential areas, genomics, communities, and modulators. The South San Francisco, California-located company was founded by Zach Sweeney in 2020.

Graphite Bio is a next-generation gene editing company focused on the development of first-in-class therapies for patients suffering from life-threatening genetic diseases. The company’s platform harnesses the natural cellular process of homology directed repair (HDR) and targeted DNA integration to precisely repair genetic defects at their source. Graphite Bio is leveraging its differentiated platform to advance a portfolio of transformative genetic treatments with potential for saving and dramatically improving patients’ lives

Centivax is a healthcare based agency that provides biotechnology, pharmaceutical, medical device manufacturing and therapeutics services.

Driverless electric vehicles at a fraction of the cost of a car.

Seranova Bio partners with clinicians and drug developers to develop companion diagnostics or therapeutics to treat autoimmune disease or other autoantibody-driven diseases. The company's REAP platform was developed to detect autoantibodies that recognize “conformational” protein epitopes (i.e., three-dimensional epitopes present when a protein is folded into its native state) which are recognized by up 90% of autoantibodies. The platform includes over 3000 extracellular and secreted proteins to comprehensively characterize autoantibody responses in patients.

Asher Bio is an information technology company that specializes in the fields of CFO Office transformation, profitability, and cost management. It focuses on building and developing better immunotherapy for cancer. The company was founded in 2019 and headquartered in San Francisco, California.

Mirvie is redefining pregnancy health by developing the first early detection RNA test to address pregnancy complications which impact 45 million women globally.

Swiftscale Biologics uses cell-free protein synthesis to enable the next generation of protein therapeutics.

Cellares is revolutionizing cell therapy manufacturing. Cellares is developing a one-of-a-kind solution, The Cell Shuttle, to overcome the challenges associated with manufacturing so these life-saving therapies are affordable and widely available to patients who can benefit.

Federation Bio is pioneering new platforms that target diseases in which the human microbiome can play a curative role.

ArsenalBio’s mission is to develop efficacious and safe cellular therapies for patients with chronic diseases, initially cancer.

We're building the leading extracellular protein degradation company leveraging our lysosomal targeting chimeras, or LYTAC, platform.

TRexBio is a discovery stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for cancer and inflammatory diseases.

Earli Inc. operates as a biotechnology company. The Company develops treatments to cure cancer. Earli serves patients in the State of California.

Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders.

Frontier Medicines’is a developer of a chemoproteomics platform intended to further accelerate the path to drug discovery. The company's platform integrates advanced computational approaches and machine learning to discover and pharmacologically target new binding pockets on proteins, making them accessible to small-molecule drug discovery and development, enabling patients to consume breakthrough medicines that redefine the course of debilitating diseases.

Aligos Therapeutics, Inc. is a clinical stage biopharmaceutical company that was founded in 2018 with the mission to become a world leader in the treatment of viral infections and liver diseases. Aligos is focused on the development of targeted antiviral therapies for chronic hepatitis B (CHB) and coronaviruses as well as leveraging its expertise in liver diseases to create targeted therapeutics for nonalcoholic steatohepatitis (NASH). Aligos’ strategy is to harness the deep expertise and decades of drug development experience its workforce has in liver disease, particularly viral hepatitis, to rapidly advance its pipeline of potentially best-in-class molecules.

Translating genetic insights into therapeutic innovations · Harnessing the potential of modern human genetics to treat disease.

Yellow is a financial services provider of software, analytics, and investments in blockchain startups.

Insitro is an operator of a data-driven drug discovery and development company that utilizes machine learning and high-throughput biology to transform the way that drugs are discovered and delivered to patients. The company uses state-of-the-art technologies from bioengineering enabling it to generate high-throughput, functional genomic data sets and aligning them with patient data via novel machine learning methods, thereby building predictive models that can accelerate target selection and the design and development of effective therapeutics. In 2018, Daphne Koller established Insitro in South San Francisco, California..

Epic Bio's strength is a relentless focus on ushering in a new era of gene regulation.

Neuron23™ Inc. is an early stage biotechnology company focused on developing precision medicines for genetically defined neurological and immunological diseases.

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Presidio Medical is a medtech company that develops a transformational neuromodulation platform. It enables people to receive remedies for disorders affecting neuronal activity.

WideTrial is a third-party sponsor of group-level Expanded Access programs (EAPs).

InterVenn focuses on the identification, quantification, and classification of Glycoproteomic and other PTM signals found in human blood and tissue for biomarker and target discovery. It specializes in the fields of biotechnology and life science. The company's VISTA is the first commercially available platform that can assess (serum or plasma) protein glycosylation in a site-specific manner, across thousands of peptides and glycopeptides. It was founded in 2017 and headquartered in Redwood City, California.

Allogene Therapeutics, Inc. operates as a biotechnology company. The Company develops allogeneic chimeric antigen receptor T-cell therapy for the treatment of blood cancers and solid tumors. Allogene Therapeutics serves patients in the State of California.

Beehive AI develops analytical tools intended to device business strategies and actions. Its tools help optimize ad messaging and targeting, enabling clients to understand which product or services add the most value.

We make delicious cheese from plant-derived dairy proteins, supporting a larger mission of creating a radically more humane and sustainable food system. Our cheese stretches, melts, and tastes as great as the ones from cows and goats-minus the animals.

Genome Medical, Inc. operates as a national telegenomics technology and services company. The Company provides virtual genetic care and services for individuals, health systems, providers and employers to improve health and well- being. Genome Medical, Inc. serves patients in the United States.

Tenaya Therapeutics, Inc. operates as a biotechnology company. The Company focuses on discovering and developing novel therapies for heart failure.

Pliant Therapeutics is focused on discovering, developing and commercializing breakthrough treatments for fibrotic diseases. By harnessing the therapeutic potential of integrin biology and TGF-β modulation, Pliant aims to prevent or even reverse fibrosis to address the needs of many patients. The company also aims to build a patient registry for certain areas of fibrotic disease to both increase understanding of natural disease progression, and fuel biomarker discovery. Pliant’s co-founders include world-renowned researchers from University of California, San Francisco (UCSF), who bring broad experience in fibrosis biology and small molecule chemistry. Together, the Pliant team is dedicated to translating scientific advances in fibrosis biology into novel therapies for patients in need.

Surrozen Inc produces and distributes pharmaceutical products. The Company develops pathway that drive tissue regeneration addressing a variety of critical unmet medical needs. Surrozen operates in the United States.

Glydways is a transportation technology and clean energy company that designs and manufactures autonomous transportation.

Therini Bio, Inc. is a biotechnology company dedicated to the research and development of novel therapeutics for the treatment of neuroinflammatory diseases due to vascular dysfunction. Our approach will be generally applicable across a range of inflammatory diseases including peripheral indication... Read more

Tizona Therapeutics, Inc., is an immunology company harnessing the power of the immune system to develop treatments for cancer and autoimmune diseases.

Enable Biosciences is a South San Francisco-based diagnostics company. They develop ultrasensitive immunoassays that permit early detection and treatment of autoimmune and infectious diseases.

IDEAYA Biosciences, Inc. operates as an oncology-focused biotechnology company. The Company develops biology and small molecule based drugs and therapeutics for the treatment of cancer. IDEAYA Biosciences serves healthcare sectors in the United States.

Harpoon Therapeutics is a clinical-stage immunotherapy company developing a novel class of T cell engagers that harness the power of the body’s immune system to treat patients suffering from cancer and other diseases. T cell engagers are engineered proteins that direct a patient’s own T cells to kil...Read more

Nkarta, Inc. operates as a biotech company. The Company develops and discovers therapies for immune systems and cancer indications. Nkarta serves patients in the State of California.

Denali Therapeutics Inc. operates as a biotechnology company. The Company discovers and develops medicines for neurodegenerative diseases. Denali Therapeutics serves patients in the State of California.

Verily Life Sciences, also known as Verily (formerly Google Life Sciences), is Alphabet Inc.'s research organization devoted to the study of life sciences. The organization was formerly a division of Google X, until August 10, 2015, when Sergey Brin announced that the organization would become an independent subsidiary of Alphabet Inc. This restructuring process was completed on October 2, 2015. On December 7, 2015, Google Life Sciences was renamed Verily.

Verge Genomics is a next-generation biopharmaceutical start-up using systems biology to accelerate development of life-saving treatments for neurodegenerative diseases.

Applied Molecular Transport Inc. operates as a biotech company. The Company develops novel therapeutics to treat severe autoimmune, metabolic, and inflammatory diseases. Applied Molecular Transport serves customers in the State of California.

Cafe X Technologies is focused on increasing productivity in the service industry through automation. Cafe X Technologies is a privately backed company with funding from Khosla Ventures, Social Capital, Jason Calacanis, Felicis Ventures, Silicon Valley Bank, and The Thiel Foundation.

Escape Bio, Inc. operates as a preclinical stage biopharmaceutical company. The Company discovers and develops small molecule drugs and medicines to treat genetically-defined subpopulations in neurodegenerative diseases. Escape Bio serves customers in the State of California.

Blade Therapeutics, Inc. operates as a biopharmaceutical company for treating fibrosis. The Company offers screening, drug discovery and development, tissue replacement, and fibrotic disease management. Blade Therapeutics conducts its business in the United States.

Encoded Therapeutics is a developer of precision gene therapies intended to provide treatment for a broad range of severe genetic disorders. The company's therapy pipeline addresses devastating genetic and acquired disorders spanning multiple disease pathways including neurocircuitry, metabolic disorders, neurodegeneration and cardiovascular disease, enabling medical practitioners to treat patients and improve their lives.

Zenflow, Inc. operates as a medical device company. The Company develops minimally invasive devices to treat obstructive urinary symptoms related to benign prostatic hyperplasia. Zenflow serves customers in the State of California.

ORIC Pharmaceuticals, Inc. operates as a pharmaceutical company. The Company discovers and develops novel therapies for the treatment of cancer diseases. ORIC Pharmaceuticals serves customers in the State of California.

Freenome, Inc. provides clinical research services. The Company develops and creates screening, diagnosis, and treatment of age-associated clinical conditions. Freenome serves patients and the healthcare sector in the United States.

Mission Bio, Inc. develops and delivers tools for the study of cellular heterogeneity. The Company offers tools for human health and life science research. Mission Bio serves customers in the State of California.

Automating Retail Simbe Robotics builds automation solutions for the retail industry. Simbe’s first product, Tally, is the world’s first fully autonomous shelf auditing and analytics solution; one that provides retailers unprecedented visibility and insight into the state of merchandise in their stores. Tally works in concert with retail associates by arming them with information to ensure the store’s products are always stocked, in the right place, and displaying the correct price tag. The company is headquartered in San Francisco, CA. For more information, please visit www.simberobotics.com or follow the company at @simberobotics

Plenty, Inc. produces food crops. The Company offers natural agricultural crops and products. Plenty serves customers in the State of California.

Alector, Inc. operates as a clinical stage biopharmaceutical company. The Company researches and develops novel therapeutics for the treatment of neurodegeneration and other brain disorders. Alector offers its services in the State of California.

TeraPore Technologies is a Cornell University spinout that develops and manufactures high performance filters for protein separations.

Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease.

Antiva Biosciences, Inc. is a clinical stage biopharmaceutical company developing novel, topical therapeutics for the treatment of diseases caused by HPV infection. They aim to stop cancer before it starts by treating the pre-cancerous lesions caused by HPV.

Claritas Rx is a digital health venture that brings clarity to the challenges of specialty biopharmaceutical products in the marketplace. In today’s highly complex specialty networks, our mission is to illuminate the patient experience beyond the clinical trial. Claritas Rx leverages a proprietary technology platform and deep manufacturer expertise to automate and integrate channel, commercial, and clinical data and help biopharmaceutical companies generate actionable business insights. Our work uncovers the real-world variables impacting patient access, duration of therapy, and other metrics key to commercial success, making a real impact on patient healthcare.

Calithera Biosciences is a development-stage pharmaceutical company committed to discovering and developing novel small molecule therapeutics for the treatment of cancer. They are applying Their scientific expertise to build a pipeline of unique anti- cancer drugs that selectively target metabolic and apoptotic pathways critical to tumor growth and survival.

Principia Biopharma Inc. operates as a clinical stage biopharmaceutical company. The Company offers reversible covalent small molecule drugs for the treatment of cancers. Principia Biopharma serves patients in the United States.

Neurona Therapeutics Inc. operates as a clinical-stage biotherapeutics company. The Company focuses on discovering and developing allogeneic neural cell therapies to treat chronic diseases of the nervous system. Neurona Therapeutics serves customers in the State of California.

Amunix Inc. is a pharmaceutical company. The Company focuses on therapeutic drugs which offer an alternative to antibodies and small molecules. Amunix also concentrates on protein design and the discovery research process.

Veracyte, Inc. develops molecular tests for oncology. The Company offers molecular cytology and tests for the diagnostic accuracy of cytology samples. Veracyte provides its products and services to healthcare and molecular diagnostic companies in the United States.

Valgenesis, Inc. designs and develops healthcare software. The Company offers equipment validation, risk management, content management, test case execution, business process modeling, integration, and support services.

Sutro Biopharma, Inc. develops and manufactures pharmaceutical products. The Company provides antibody drug conjugate and multi-specific antibody-based therapeutics for cancer therapy. Sutro Biopharma serves the pharmaceutical industries throughout the United States.

Nodality develops biologically-informed clinical treatments for patients with cancer and autoimmune diseases.

Diadexus is a post-genomics company focused on translating raw genomics data into novel diagnostic and therapeutic products. The company develops these diagnostic and therapeutic products for improved detection, classification and prognosis of diseases.

Catalyst Biosciences, Inc. operates as a biopharmaceutical company. The Company develops novel medicines to address hematology indications, as well as deals in treatment of hemophilia and surgical bleeding. Catalyst Biosciences serves patients in the United States.

Genentech, Inc., is an American biotechnology corporation which became a subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within Roche. Historically, the company is regarded as the world's first biotechnology company.