COMPANY PROFILE · UPDATED 01 AUG 2026

Denali Therapeutics

Denali Therapeutics Inc. operates as a biotechnology company. The Company discovers and develops medicines for neurodegenerative diseases. Denali Therapeutics serves patients in the State of California.

South San Francisco, CA

denalitherapeutics.com ↗

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Healthcare & Biotech Biotech & Drug Discovery Medical Organizations Health Care Companies Health Care Companies In San Francisco Medical Organizations In San Francisco Biotechnology CompaniesPost Ipo Equity

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Founded: 2015
Headcount: 158
Open roles: 0
Last raised: Post Ipo Equity

LOCATIONS

Where they work

Denali Therapeutics offices

South San Francisco, CA151 Oyster Point Blvd suite 400

FUNDING

Capital raised

Total raised

$2,017,423,000

Investors

Funding rounds

Post Ipo Equity
$250MMar 17, 2026
Post Ipo Debt
Royalty Pharma
$200MDec 4, 2025
Post Ipo Equity
Longitude Capital, OrbiMed Advisors, Vivo Capital, Venrock Healthcare Capital Partners, RTW Investments
$100MMay 11, 2025
Post Ipo Equity
$500MFeb 27, 2024
Post Ipo Equity
$275MOct 19, 2022
Post Ipo Equity
$93.6MJan 20, 2021
Post Ipo Equity
$116.9MJul 9, 2018
Series B
Baillie Gifford & Co, Alaska Permanent Fund, Flagship Pioneering, F-Prime Capital, Arch Venture Partners
$130MAug 25, 2016
Series D
Casdin Capital, Cormorant Asset Management, Perceptive Advisors, Redmile Group, Venrock, Wellington Management, Tekla Capital Management, Deerfield Management
$70MJun 15, 2015
Series A
Alaska Permanent Fund, Arch Venture Partners, Flagship Pioneering, F-Prime Capital, Biomatics Capital Partners, Eight Roads
$217MMay 14, 2015
Series C
Pfizer Venture Investments, Third Rock Ventures, Canaan Partners, Roche Venture Fund
$20MJan 5, 2015
IPO
UndisclosedJan 1, 2015
Series B
$1.4MApr 28, 2014
Series B
Canaan Partners, Third Rock Ventures
$11MJul 30, 2012
Series B
Third Rock Ventures, Roche Venture Fund
$30MSep 22, 2010
Convertible Note
Mike Panesis
$2.5MMar 2, 2010

Funding data via Diffbot, SEC EDGAR filings and company announcements — a round from a filing or announcement links to it

OPEN ROLES

Roles at Denali Therapeutics

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LEADERSHIP