Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications. | Waltham | MA | 4 | 2024 | $797,600,000 |
Kailera Therapeutics is a clinical-stage biotechnology company that provides revolutionary therapies for treating obesity and related diseases. | Waltham | MA | 50 - 200 | 2024 | $1,000,000,000 |
We know that drug development is both an art and a science. The work we do is incredibly technical, intentional, and specific, but there is an art to it - because we must leave room for creativity, innovation and spontaneity. Murals are paintings that transform overlooked or unused spaces - creating something impactful and meaningful. There remains many overlooked opportunities in cancer drug development. This is what inspires us. Our mission is simple, to create novel immunotherapies that can change patients’ lives so they can get back to what matters most - living. Mural Oncology is leveraging its industry-leading protein engineering platform to revolutionize cytokine-based immunotherapies for the treatment of cancer. Immunotherapies have been transformative for some people living with cancer, but unfortunately many patients still do not benefit - either because they are ineligible for treatment or they do not respond well to current therapies. We leverage our expertise in cytokine biology, immune cell modulation and our protein engineering capabilities to develop first and novel immunotherapies. Our goal is to deliver meaningful, clinical benefit across a wide range of cancers, including tumor types where immunotherapies have previously not been effective. Mural Oncology is developing a portfolio of programs to broaden the potential and reach of cytokine-based immunotherapies for the treatment of cancers. (NASDAQ: MURA) | Waltham | MA | 50 - 200 | 2023 | $275,000,000 |
Customer Experience (CX) leaders are constantly in reactive mode, but Perch empowers them with data-driven insights to work proactively, leading to progressively better business decisions to expand customer lifetime value and minimize customer acquisition and service costs. No other CX business intelligence platform structures data from multiple data sources such as CRMs and customer service platforms, contact center applications, chatbots, marketing platforms, and HR systems into a single source of truth and then provides actionable insights like Perch. Perch offers the best way for CX leaders and their colleagues across the enterprise to see the forest through the trees to increase market share and improve the customer journey. | Waltham | MA | 20 - 50 | 2022 | $2,900,000 |
Monaire is an electronics manufacturing company that offers HVAC and refrigeration management service for small businesses. | Waltham | MA | 10 - 20 | 2022 | $7,639,996 |
Swipe through short videos on data science from industry experts and peers | Waltham | MA | 200 - 500 | 2021 | $25,200,000 |
Koverly is redefining the standard of global payments. Foreign exchange without all the fees + credit platform built for importers. | Waltham | MA | 10 - 50 | 2021 | $26,552,489 |
Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma. They are clinical-stage monoclonal antibodies that inhibit the TSLP receptor, a validated target located upstream of various signaling cascades that influence a range of immune cells that are important in common and unusual illnesses. | Waltham | MA | 50 - 100 | 2021 | $408,000,000 |
SeQure DX is in the business activities at non-commercial site business. | Waltham | MA | 20 - 50 | 2021 | $17,500,000 |
Basecamp Bio is a cell and gene therapy research and development company that develops cell and gene therapies, regenerative medicine, and immunotherapies. | Waltham | MA | 10 - 50 | 2021 | $14,000,000 |
Adagio Therapeutics is developing best-in-class antibodies that can broadly neutralize SARS-CoV-2, SARS-CoV-1, and additional potentially emergent coronaviruses. They believe that antibodies will match or exceed the potency and coverage of conventional SARS-CoV-2 antibody programs and can be used as both therapeutic and durable prophylactic treatments. Their candidates are engineered using best-in-industry antibody discovery capabilities and are designed to maximize potency and duration of effect. Their portfolio includes multiple, non-competing antibodies with distinct binding targets, enabling a strategy that can avoid viral escape. | Waltham | MA | 99 | 2020 | $678,500,000 |
Zenas BioPharma is a cross-border (China-USA-based) biopharmaceutical company committed to becoming a global leader in the development and delivery of immune-based therapies for patients in China and around the world. Zenas is rapidly advancing a deep pipeline of innovative therapeutics that continu... Read more | Waltham | MA | 100 - 500 | 2020 | $813,000,000 |
Pretzel was founded by some of the world’s foremost academics in mitochondrial biology, and we benefit from the leadership of accomplished experts in drug discovery, drug development, and company formation. Our name is inspired by the focal point of our science, the mitochondrion, whose highly folded inner membrane is one of many fascinatingfeatures that make it unlike any other organelle in the body. | Waltham | MA | 20 - 100 | 2019 | $72,500,000 |
Verana Networks develops an innovative 5G Radio Access Network solution for service providers that have licensed millimeter wave (mmWave) spectrum. The company focuses on enabling 5G in mmWave spectrum because that is where the largest amount of new spectrum is. For 5G to succeed, it must deliver a 10X-50X increase in speed and capacity. Blazing fast speed and an increase in capacity enable new applications, these new applications create incremental revenue, and incremental revenue is essential to support the business case for 5G. | Waltham | MA | 20 - 100 | 2019 | $52,550,000 |
Vet's Best Friend was founded in February 2019 to create a people-focused veterinary platform in the Northeast that enables selling veterinarians and pet caregivers to provide the highest quality of care while also promoting a culture of ''taking care of the people who take care of your pets.'' VBF differentiates itself from other consolidation strategies by focusing on the personal and professional development of every employee while also allowing for clinical autonomy within the guidelines of medical best practices. | Waltham | MA | 5 - 20 | 2019 | $76,000,000 |
Ventus Therapeutics is a biopharmaceutical company discovering and developing novel small molecule medicines that target the innate immune system to treat autoimmune diseases, inflammatory diseases, and cancer. Ventus' structural immunology platform offers unprecedented insight into mechanisms and molecular structures, combining core capabilities for precisely targeting the innate immune system: proprietary protein engineering capabilities that elucidate innate immune mechanisms, and leading-edge rational and structure-based drug design tools. Ventus has built an emerging pipeline of multiple drug programs addressing key targets in the innate immune system. | Waltham | MA | 20 - 100 | 2019 | $370,150,016 |
The Noble Pursuit of Reliable Software. Nobl9’s service level objective (SLO) platform for site reliability engineers (SRE) helps software teams release reliable features faster. | Waltham | MA | 50 - 100 | 2019 | $44,299,985 |
Affinia Therapeutics is working to methodically engineer durable gene therapies for people with devastating diseases. | Waltham | MA | 50 - 100 | 2019 | $210,000,000 |
Dyne Therapeutics, Inc. operates as a biotechnology company. The Company focuses on transforming the lives of people with serious diseases by developing muscle-targeted therapies for muscle disorders such as myotonic, duchenne, and facioscapulohumeral muscular dystrophy. Dyne Therapeutics serves patients in the United States. | Waltham | MA | 258 | 2018 | $1,672,600,000 |
Randori is your trusted adversary. Our Attack Platform empowers organizations with a continuous and automated red team experience they can use to assess their real-world security. By mirroring today’s adversaries, we help security teams identify gaps, demonstrate effectiveness, and get better over time. Headquartered in Waltham, MA, with offices in Denver, CO, the company is backed by .406 Ventures, Accomplice, Harmony Partners and Legion Capital. | Waltham | MA | 50 - 100 | 2018 | $29,750,000 |
Vecna Robotics, Inc. provides robotics solutions. The Company offers automated material handling, hybrid fulfillment, and workflow optimization solutions. Vecna Robotics serves clients in the United States. | Waltham | MA | 100 - 200 | 2018 | $213,999,993 |
Devoted Health, Inc. provides health care services. The Company offers health care plan and navigates health care systems with personal guides. Devoted Health operates in the State of Massachusetts. | Waltham | MA | 1,000 - 2,000 | 2017 | $2,622,000,000 |
KnowYourMeds is a digital health app that uses the world’s largest database of suspected side/adverse effects along with AI driven insights to inform patients and improve health outcomes through better adherence, early identification of drug interactions and early detection of potential medication errors.
Every year, millions of patients show up at Emergency Rooms with medicine related issues, and over 40% of these cases are shown to be preventable if only the patient had better access to information (digital as well as human interactions).
Medicine related incidents arise from multiple reasons:
1) Adverse reactions to drug/s being taken
2) Self-medication to treat adverse reactions rather than seeking help for underlying causes
3) Interactions between various drugs being taken
4) Adverse drug interactions with diets, alcohol
5) Dosage instructions not followed properly
6) Duplication of drugs being taken due to lack of knowledge
7) Wrong drug being taken, especially self-medication with OTC drugs
8) Drug overdoses, either due to addiction or lack of knowledge
9) Lack of compliance - forgetfulness, distractions, changes in routines
KnowYourMeds is available on the iPhone, iPad and Android devices as well as at www.knowyourmeds.com | Waltham | MA | 5 - 20 | 2017 | |
Alloy Therapeutics is a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. We provide affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.
Our lead offering, the ATX-Gx™ platform, is a human therapeutic antibody discovery platform consisting of a growing suite of proprietary transgenic mice strains.
Founded in 2017 and privately funded by visionary investors, we are headquartered in Boston, MA with European labs in Cambridge, UK.
As a reflection of our relentless commitment to the scientific community, Alloy reinvests 100% of its revenue in innovation and access to innovation.
Learn more by scheduling a time to speak with our BD team: https://www.alloytx.com/bd | Waltham | MA | 50 - 200 | 2017 | $168,250,000 |
Dover Microsystems, Inc. provides software and hardware solutions. The Company offers application to stop and eliminate network-based cyberattacks, as well as to defend from security, safety, and privacy risks. Dover Microsystems serves customers in the State of Massachusetts. | Waltham | MA | 5 - 20 | 2017 | $6,000,000 |
NAVERIS is to deliver innovations in technology with the potential to transform cancer detection, drug development, and clinical trials. | Waltham | MA | 20 - 100 | 2017 | $66,334,833 |
Spectrawave is a medical device company that develops optical diagnostic and therapeutic devices.It enhances the diagnosis and treatment of cardiovascular diseases and primarily operates in the diagnostic equipment, medical business/industry.The Waltham, Massachusetts based company was founded in 2017. | Waltham | MA | 20 - 50 | 2017 | $79,597,066 |
Nocion Therapeutics is a biopharmaceutical company developing novel treatments for silencing neurons. | Waltham | MA | 5 - 20 | 2017 | $133,999,994 |
Veo Robotics is transforming manufacturing with products that incorporate advanced computer vision, 3D sensing, and AI. Their first product lets high-performance industrial robots work collaboratively with people to enable much more flexible, productive, and efficient manufacturing workcells. | Waltham | MA | 10 - 50 | 2016 | $57,000,000 |
Avava is a Pioneer precision skin therapy to improve the quality of life for patients around the world. | Waltham | MA | 10 - 50 | 2016 | $58,816,033 |
Takeoff is helping grocers thrive in e-Commerce. Its automated grocery fulfillment solution was created by grocers, for grocers. It is the only eGrocery model that helps grocers not only embrace eGroceries, but thrive in an online grocery market. Together, it can lower users' last-mile and assembly costs, giving them the flexibility that they need to grow with their customers. The time is ripe for e-Groceries! | Waltham | MA | 10 - 500 | 2016 | $146,131,344 |
Uptycs, Inc. provides software security solutions. The Company offers security analytics platform for fleet visibility, intrusion detection, vulnerability monitoring, and compliance across operating systems and computing environments. Uptycs serves customers in the State of Massachusetts. | Waltham | MA | 200 - 500 | 2016 | $93,000,000 |
Xilio Therapeutics, Inc. operates as a biotech company. The Company focuses on developing tumor-targeted immuno-oncology therapeutics. Xilio Therapeutics serves medical sector in the United States. | Waltham | MA | 76 | 2016 | $370,100,000 |
6 River Systems, Inc. operates as a robotics fulfillment solution provider. The Company offers a product which uses a mobile robot and cloud-based enterprise software to improve warehouse staff productivity and simplify training. 6 River Systems serves direct to consumer, retail store replenishment, and service parts fulfillment operations in North America. | Waltham | MA | 50 - 500 | 2015 | $46,000,000 |
Global 2000 companies use GreatHorn to reduce the inherent and pervasive risk associated with the everyday use of email. GreatHorn’s multi-staged approach to email security automatically combines data science, machine learning techniques, and technical analysis with human context to protect organizations before, during, and after a phishing attack.
By treating email security as a risk management function, customers can not only detect and remove more attacks but also warn users in real-time of potential threats and provide response teams with the tools to limit exposure and minimize risk. As a result, GreatHorn Email Security safeguards cloud email from advanced threats such as business email compromise, impersonations, credential theft, account takeover, and other phishing attacks.
More information can be found at http://www.greathorn.com | Waltham | MA | 10 - 50 | 2015 | $22,203,030 |
Medical technology company based in Waltham, Massachusetts, USA | Waltham | MA | 100 - 200 | 2015 | $232,849,013 |
Humatics Corporation provides microlocation system and analytics software solutions. The Company offers radio-frequency technology to pinpoint and move transponder targets, as well as to locate, navigate, and collaborate people and machines. Humatics serves customers in the State of Massachusetts. | Waltham | MA | 20 - 100 | 2015 | $80,215,000 |
BostonGene Corporation is pioneering the use of biomedical software for advanced patient analysis and personalized therapy decision making in the fight against cancer. BostonGene’s unique solution performs sophisticated analytics to aid clinicians in their evaluation of viable treatment options for each patient's individual genetics, tumor and tumor microenvironment, clinical characteristics and disease profile. BostonGene’s mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies | Waltham | MA | 100 - 500 | 2015 | $200,000,000 |
Vicarious Surgical Inc. provides health care services. The Company offers minimally invasive robotic surgery through a single micro-incision. Vicarious Surgical serves patients in the State of Massachusetts. | Waltham | MA | 123 | 2014 | $236,050,000 |
Cazena was founded by former Netezza leaders with a mission to radically simplify and speed up access to big data, allowing much faster business outcomes at a fraction of the cost. | Waltham | MA | 10 - 50 | 2014 | $38,000,000 |
connectRN connects the nursing community with opportunities - and each other - to build a supportive and thriving network. The company was founded in 2014 and is based in Waltham, Massachusetts, United States. | Waltham | MA | 50 - 200 | 2014 | |
General Fluidics develops an in vitro diagnostic tool for performing a growing array of blood and urine tests. Its platform uses a patented hybrid hardware architecture, fluidics, and optoelectronic technologies to go beyond test results to deliver complete diagnostic information sets at the point of care. | Waltham | MA | 5 - 20 | 2014 | $30,514,740 |
NanoSemi develops intellectual property based upon machine learning to improve communication and other systems. | Waltham | MA | 10 - 50 | 2014 | |
About Plataine: Plataine is the leading provider of Industrial IoT and AI-based optimization solutions for advanced manufacturing. Plataine’s intelligent, connected Digital Assistants take manufacturing to the next level by automating and optimizing decision flows on the production floor. Combining state-of-the-art AI with extensive manufacturing knowledge, Plataine’s cloud-based solutions continually assess current status and predict future events on the production floor, to provide actionable insights, alerts and recommendations, empowering production management and staff to make optimized decisions in real-time, every time. Plataine enables global manufacturers to drive digital transformation and further increase the business value they generate from our offerings. Plataine’s patent-protected technologies are used by leading manufacturers worldwide, including Airbus, GE, IAI, Triumph, Stelia North America, Alestis, Enercon, TPI, Kineco-Kaman, IFS, Light & Strong and Ethan Allen. Plataine partners with SAP, Siemens PLM the Advanced Manufacturing Research Centre (AMRC) with Boeing, and CTC GmbH (an Airbus Company), and is also a part of the UK National Composites Centre (NCC) membership network, to advance the ‘Factory of the Future’ worldwide. For this work, Plataine has received Frost & Sullivan’s 2021 Global Technology Innovation Leadership Award for its AI-Based Digital Assistants for Manufacturing and Innovation Awards from the JEC, Plataine Receives SME 2021 Excellence in Composites Manufacturing Award and CompositesUK organizations. Plataine is ISO 27001 certified for compliance with information security management requirements. For more information, visit: www.plataine.com | Waltham | MA | 10 - 100 | 2013 | |
Kiora Pharmaceuticals, Inc. operates as a clinical-stage specialty pharmaceutical company. The Company focuses on developing and commercializing products for treating ophthalmic diseases. Kiora Pharmaceuticals serves customers worldwide. | Waltham | MA | 13 | 2013 | $111,492,568 |
Evolv Technologies Holdings, Inc. operates as a holding company. The Company, through its subsidiaries, develops AI-based touch-less screening technologies for weapons detection, identity verification, and health-related threats. Evolv Technologies Holdings serves customers worldwide. | Waltham | MA | 287 | 2013 | |
Creativestar Is An Incubator, Accelerator, And Investor. They Support The Development Of Great Business Ideas And Accelerate Growth Of Great Companies By Leveraging Their Unique Resources From The World’S Two Largest Economies: The United States And China. | Waltham | MA | 10 - 50 | 2013 | |
The company the develops and provides support for HAProxy | Waltham | MA | 10 - 200 | 2013 | |
TrapX Security Inc. develops software. The Company offers cyber security defense solutions to detect, analyze, and defeat malicious insiders. TrapX Security serves healthcare, technology, manufacturing, and financial sectors worldwide. | Waltham | MA | 20 - 50 | 2012 | $47,710,000 |
KALA BIO, Inc. operates as a clinical-stage biopharmaceutical company. The Company designs and develops proprietary drug delivery technology to penetrate mucosal tissue such as the eyes, lungs, gastrointestinal tracts, and the female reproductive systems. KALA BIO markets its products worldwide. | Waltham | MA | 6 | 2009 | $580,619,845 |
Glenrose Instruments Inc. provides waste management services. The Company offers collection and disposal of refuse systems, remediation, environmental, safety, and health management services for nuclear sites. Genrose Instruments serves government agencies in the United States. | Waltham | MA | 200 - 500 | 2005 | $14,880,000 |
Dynatrace, Inc. is a global technology company listed on the NYSE that provides a software intelligence platform based on artificial intelligence (AI) and automation to monitor and optimize application performance, software development and security practices, IT infrastructure, and user experience for businesses and government agencies throughout the world. | Waltham | MA | 5,200 | 2005 | $21,900,000 |
Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases. | Waltham | MA | 20 - 50 | 2004 | $455,000,000 |
CallMiner is a Massachusetts-based software company that develops speech analytics and interaction analytics software. It was founded in 2002 and is headquartered in Waltham, MA with offices in Fort Myers, FL, Boston, MA, and the United Kingdom. The company uses Artificial Intelligence to extract insight from the conversations that occur between businesses and their customers, typically through the contact center. These conversations can be voice-based and occur over the phone, or text-based and occur over digital mediums such as online, chat, email, social media messaging, and more. As of December 2019, CallMiner has raised six rounds of venture funding. Its largest and latest investment was 2019’s funding from GS Growth, an investment unit of Goldman Sachs. | Waltham | MA | 200 - 500 | 2002 | $196,610,887 |
Automate accounts receivable with branded invoices and payment links. Leverage templates and content libraries for efficiency. Enable automatic payments, apply late fees, offer payment plans and more. | Waltham | MA | 100 - 500 | 2002 | $165,035,008 |
Protara Therapeutics, Inc. operates as a biotech company. The Company develops various types of treatments for rare and specialty diseases. Protara Therapeutics serves customers in the State of New York. | Waltham | MA | 46 | 2001 | |
Invoke Solutions offers real-time online research services that provide efficient, usable insights for their clients. | Waltham | MA | 10 - 100 | 1999 | $22,300,000 |
Buyers Edge Platform is your data driven foodservice supply chain, contracting and purchasing partner. It is a purchasing network of tech-enabled GPOs, Saas companies and supply chain consultants that create unparalleled efficiency and new value in the foodservice channel. | Waltham | MA | 200 - 500 | 1998 | $425,000,000 |
Constant Contact, Inc. is an online marketing company, headquartered in Waltham, Massachusetts, with additional offices in Loveland, Colorado; and New York, New York. | Waltham | MA | 1,000 - 2,000 | 1995 | $423,159,714 |
Boston Dynamics is an American engineering and robotics design company founded in 1992 as a spin-off from the Massachusetts Institute of Technology. | Waltham | MA | 500 - 2,000 | 1992 | $37,000,000 |