Arcus Biosciences, Inc. operates as a biotechnology company. The Company discovers, develops, and commercializes immunotherapies for the treatment of cancer patients. Arcus Biosciences serves customers in the United States.

Arcus Biosciences

Kate Falberg

Andy Perlman

Terry Rosen

Doxil

Apellis Pharmaceuticals

ITeos

Organization based in Bangalore, Karnataka, India

RHHBY

Roche

TIGIT Drug Tecentriq

Arcus Biosciences is an oncology-focused clinical-stage biopharmaceutical company that discovers, develops, and commercializes novel therapies for the treatment of cancer. It aims to create new cancer therapeutics through the utilization of emerging insights in immunology. The company has four molecules in clinical development: Etrumadenant (AB928), the first dual A2a/A2b adenosine receptor antagonist to enter the clinic, is being evaluated in multiple Phase 2 and 1b studies across different indications, including prostate, colorectal, non-small cell lung, pancreatic and triple-negative breast cancers. AB680, the first small-molecule CD73 inhibitor to enter the clinic, is in Phase 1/1b development for first-line treatment of metastatic pancreatic cancer in combination with zimberelimab and gemcitabine/nab-paclitaxel. Domvanalimab (AB154), an anti-TIGIT monoclonal antibody and new potential immuno-oncology backbone therapy, is in a three-arm randomized Phase 2 study for first-line treatment of PD-L1-high metastatic non-small cell lung cancer (NSCLC) evaluating zimberelimab monotherapy, domvanalimab with zimberelimab and domvanalimab plus AB928 with zimberelimab. AB308, an anti-TIGIT antibody that is FcR enabled, is advancing into clinical development to investigate additional indications, with a focus on hematological malignancies. Zimberelimab (AB122), Arcus’s anti-PD-1 monoclonal antibody, was in-licensed to enable the development of Arcus’s combination regimens and is being evaluated in various combinations across the portfolio. Arcus was formed in 2015 in Hayward, California by Terry Rosen and Juan Jaen.

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Medical Organizations

Pharmaceutical Companies

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Juan Jaen

Manufacture of pharmaceuticals, medicinal chemical and botanical products

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Hayward

City in Alameda County, California, United States

United States of America

San Francisco Bay Area

Metropolitan area in California, United States

California

Alameda County

Manufacture of basic pharmaceutical products

Manufacture of pharmaceutical preparations

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Arcus Biosciences

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