SECTION I · THE BRIEF
Brief #87020Updated 15 SEP 2026SOUTH SAN FRANCISCO, CARippling
Employbl Company Profile

Senior/Staff RD System Integration Scientist - Electrochemical Enzymatic DNA Synthesis

Atlas Data Storage is pioneering the use of DNA as a highly durable, low cost permanent data storage medium.

Location
South San Francisco, CA
Company size
10–50
Posted
3w ago
Via
Rippling
Section II · Full ProfileFree with an account
  • 01Comp band & equity packageLocked
  • 02Seniority & experience requirementsLocked
  • 03Interview process & rubricLocked
  • 04Hiring manager & team contextLocked
  • 05Growth trajectory in this roleLocked
  • 06Offer & decision timelineLocked

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Senior/Staff RD System Integration Scientist - Electrochemical Enzymatic DNA Synthesis

AtlasBase· South San Francisco, CAView company profile


Job title
Senior/Staff RD System Integration Scientist - Electrochemical Enzymatic DNA Synthesis
Job location
South San Francisco, CA
Job description

About the role

In this pivotal role, you will serve as the cross-functional technical lead bridging chemistry, surface science, microfluidics, software automation, and CMOS hardware. You will own the hands-on system integration of prototype testbeds, custom software scripts, and fluidic controls to reliably execute enzymatic DNA synthesis on chip. You will drive platform performance from early-stage research integration through product-facing integration, process documentation, and technology transfer.

Responsibilities

  • Serve as a major contributor to the development, optimization, and system-level troubleshooting of CMOS chip-based enzymatic DNA synthesis workflows and electrochemical synthesis protocols, including chip handling, hardware configuration, and software integration.
  • Drive the assay-to-instrument translation of complex enzymatic synthesis and electrochemical deblock onto automated CMOS chip-based synthesis platforms.
  • Execute rigorous failure-mode analysis to systematically identify, diagnose, and resolve multi-variable root causes across hardware, fluidics, surface chemistry, and electrochemistry.
  • Establish experimental and operational strategies to maximize enzymatic DNA synthesis workflow robustness, repeatability, and synthesis fidelity on integrated breadboard and prototype testbeds.
  • Collaborate closely with hardware engineering and software teams to improve, and iterate prototype testbeds, integrating chemistry, fluidics, and hardware systems.
  • Analyze complex experimental data using molecular biology, organic chemistry techniques, and automated scripting tools.
  • Drive technology transfer from early-stage research integration to product-facing integration.
  • Help define and execute scientific and technical objectives aligned with company goals, while mentoring junior research associates and engineers.

Qualifications

  • Advanced degree (Ph.D. or M.S.) in Electrochemical Engineering, Chemical Engineering, Biomedical Engineering, Fluidic Engineering, Chemistry, or a closely related discipline.
  • Minimum 8 years of industry R&D experience for candidates holding a Master's degree or minimum 5 years of industry R&D experience for candidates holding a Doctoral degree.
  • Demonstrated track record of leading assay-to-instrument translation, taking novel bio-hardware, microfluidics, surface chemistry, or single-molecule/microarray platforms through early research into product development.
  • Extensive experience in system-level troubleshooting and failure-mode analysis across complex bio-instrumentation, fluidics, and bio-electronic interfaces.
  • Proven capability in evaluating and optimizing biological workflow robustness to ensure reproducible performance across automated platforms.
  • Proven track record of leading multidisciplinary project teams or direct management and mentorship of junior scientist and research associates.
  • Creative and detail-oriented personality with exceptional analytical, verbal, and written communication skills.
  • Exceptional collaboration skills and ability to work seamlessly in a dynamic and fast-paced environment.

Preferred Qualifications & Bonuses

  • Deep, hands-on expertise in advanced electrochemical techniques (e.g., cyclic voltammetry, electrochemical impedance spectroscopy, ac voltammetry, chronoamperometry) and sensor characterization on solid substrates.
  • Direct hands-on experience with enzymatic DNA synthesis chemistries, oligonucleotide microarray platforms, or single-molecule biosensing instruments.
  • Practical proficiency with Python, or software scripting tools for instrument automation, liquid handling, hardware control, or pipeline data processing.
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AtlasBase headquarters

South San Francisco, CA

Company size

10–50 employees

Founded

2025

Total raised

$155,000,000

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