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Sr. Operations Manager - Mantra Bio

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Job Title
Sr. Operations Manager
Job Location
South San Francisco, California, United States
Job Description

About Mantra Bio

At Mantra Bio we seek to create better medicines by developing next generation biologics based on our leading proprietary exosome engineering platform, REVEAL™. REVEAL™ integrates in silico computational biology and wet-lab automation to enable the rational design of engineered exosome therapeutics directed at a wide range of tissue and cellular targets. The foundation of our success is our truly interdisciplinary team who work collaboratively to accelerate therapeutic development. As a team, we value Self-Empowerment, Candor, Curiosity, and Collaboration and consider our human-centric culture to be our most important asset. We are proud to count 8VC, Viking, Samsung Securities, Illumina, Allen & Company and TenCent among our investors. Mantra Bio operates out of a newly constructed state-of-the-art facility in Oyster Point, South San Francisco.

About the Role

We are seeking a highly creative, passionate, and motivated individual to join us in the development of the next generation of Exosome-based therapeutics. As Sr. Operations Manager , you will lead our operations team and work closely with our scientific teams and onsite staff. In this position, you will be a key contributor to ensuring Mantra Bio has the operational strategy and efficiency  to support the company’s fast-paced growth. You will manage and oversee our daily lab and facility operations, and work closely with leadership to develop projects to increase operational efficiency. You will be responsible for leading major capital projects such as facility roadmapping, new facility  build-outs, and large CapEx equipment purchases as well as managing external vendors and service providers. To be successful in this role you must have  experience in growing and developing operational teams and processes in a fast-paced biotech environment. being strategically minded, service-oriented, and deeply knowledgeable  of biotechnology lab and facility operations is a must. Lastly, you should have a passion for working collaboratively with a cross-disciplinary team to create an operational environment that is safe, engaging, and effective. 


  • Oversee day-to-day lab operations including procurement & vendor management, safety & compliance, equipment & waste stream management 
  • Oversee our day-to-day facility operations including accounting, shipping and receiving and office management.
  • Lead and develop the Lab and Facilities Operations team, by providing strategic direction, technical supervision, and individual career development support.
  • Improve Mantra Bio’s Procurement process &  Vendor management to optimize the use of resources while maintaining efficient operations 
  • Identify new opportunities for optimizing lab and office processes
  • Manage comprehensive Environment, Health & Safety (EHS) program including hazardous materials management.
  • Lead and support major capital projects such as facility build outs and Capex acquisition.
  • Maintain all pertinent permits & be the liaison to commercial property managers

Your profile:

  • 3-6+ years of experience in operations management in Biotech and Pharmaceutical industry with 1-3+ years prior personnel management experience 
  • Process-oriented, strategic thinker with a track record of thriving in dynamic work environments and flexibly developing an organization from an operational perspective
  • Experience in working with Leadership as well as a strong ability to influence key stakeholders, drive change, and achieve support for new initiatives across the company
  • Experience managing external vendors and service providers for all operations projects and programs
  • Excellent ability to manage multiple tasks, prioritize, and meet required deadlines
  • Knowledge of pertinent health and safety laws and regulations
  • Excellent communication skills
  • Bachelor’s Degree required. 

Annual Salary for this role - $115,000 - $145,000

Mantra Bio’s Culture:

At Mantra Bio, we value Self-Empowerment, Candor, Curiosity, and Collaboration. We take pride in being a human centric, collaborative work place that brings humble and wildly intelligent people together to build the next revolution in therapeutics. We believe that a great team makes a successful company and we trust each team member to do what’s best for the organization. We believe that a culture of feedback in an environment of empathy and respect is essential to cultivating curiosity and learning, while also leading to personal growth and the growth of our organization.  We love handing out Kudos, being creative, and celebrating our success together. We are committed to creating a diverse and inclusive environment and we are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.


  • Comprehensive health benefits package
  • 401k
  • Meaningful stock option grants
  • Flexible PTO and year-end shutdown
  • Generous Parental Leave program
  • Growth-oriented professional development opportunities
  • Team-building events
  • Fully stocked kitchen

Mantra Bio Headquarters Location

San Francisco, CA

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Mantra Bio Company Size

Between 20 - 50 employees

Mantra Bio Founded Year


Mantra Bio Total Amount Raised


Mantra Bio Funding Rounds

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  • Series A

    $9,000,000 USD

  • Series A

    $25,000,000 USD

Mantra Bio's Investors