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Senior Scientist, Computational Biologist - Cancer Biology - Harbinger Health

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Job Title
Senior Scientist, Computational Biologist - Cancer Biology
Job Location
Cambridge, MA
Job Description

Harbinger Health is pioneering the detection of early cancer and enabling foundationally new approaches to cancer screening, diagnosis, and management. Incubated within Flagship Pioneering for three years before launching in 2021, Harbinger combines advances in artificial intelligence with proprietary insights into the biology of early cancer cell formation to identify cancer before it is visible or symptomatic with the aim of developing low-cost, multi-cancer blood tests.

At Harbinger, we intend to lead in shaping this future – creating a proactive paradigm so that people can live cancer-free for longer, adding years to life and life to years. We envision a future where, instead of keeping cancer from spreading, it could be kept from forming, making a cancer diagnosis a routine health problem to be addressed rather than a life-altering event to be feared with profound implications for people, healthcare systems and societies.

Our answer starts with proprietary solutions we are developing with our platform technology.  By making cancer screening accessible on a global scale, Harbinger Health has the potential to fundamentally change cancer care, for everyone.

Our lifesaving work is grounded by our principles of rigor and transparency, constructive engagement, inclusiveness, accountability and quality, and a strong commitment to our customers, patients, and each other.  These values drive our decisions and actions. We are a highly dynamic, entrepreneurial, and innovation-driven organization seeking collaborative, passionate, and dedicated people to join our team.

Position Summary

As a Senior Scientist, Computational Biology – Cancer Biology at Harbinger Health, you will work collaboratively across all technical teams bringing expertise within cancer biology and NGS data analysis. You will develop cutting-edge bioinformatics algorithms to distill complex genomic data into actionable insights. Leveraging your experience with multi-omics data analysis focusing on epigenetic and/or methylation data, you will help further our understanding of cancer and advance our detection capabilities through comprehensive genomic analysis.


  • Collaborate within an interdisciplinary team to innovate diagnostic products using massively parallel DNA or RNA sequencing from liquid biopsy samples.
  • Spearhead the creation of computational methods aimed at cancer detection, treatment response monitoring, and identifying minimal residual disease.
  • Refine and enhance current methodologies to bolster assay functionality and robustness.
  • Analyze and interpret extensive datasets to uncover the intricacies of Harbinger's core biology.
  • Effectively communicate scientific findings to internal teams, ensuring clarity and cohesion.
  • Independently manage project timelines, deliverables, and schedules.
  • Act as a computational biology representative in cross-functional project teams.
  • Execute additional responsibilities as needed to support the team’s objectives.

Basic Qualifications

  • Ph.D., M.S. in Bioinformatics, Computational Biology, Data Science, Computer Science, or related field.
  • 3+ years' experience in NGS-based diagnostics or genomic research.
  • 2+ years' academic or professional experience in molecular biology, cancer biology, or genomics.
  • Proficient in programming and scripting languages such as Python, R, or Java.
  • Proven track record in:
    • Algorithm development for biological data analysis.
    • NGS data, particularly DNA methylation sequencing.
    • Data science methodologies and tools, including Pandas, Jupyter, AWS cloud services, and machine learning approaches.
    • Collaborating with laboratory scientists to support experimental design and bioinformatics analysis.
    • Managing and leading collaborative projects.
  • A robust understanding of molecular biology and genomics.
  • Exceptional teamwork, time management, and organizational capabilities.
  • Demonstrated independence in a multidisciplinary, fast-paced environment.
  • Effective communication skills, with experience presenting complex data to diverse audiences.

Preferred Qualifications

  • Experience developing regulated diagnostic products.
  • Knowledge of HIPAA and commitment to patient data privacy.

Harbinger Health is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Harbinger Health does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Harbinger Health or its employees is strictly prohibited unless contacted directly by Harbinger Health’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Harbinger Health, and Harbinger Health will not owe any referral or other fees with respect thereto.

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Harbinger Health Headquarters Location

Cambridge, MA

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Harbinger Health Company Size

Between 50 - 100 employees

Harbinger Health Founded Year


Harbinger Health Total Amount Raised


Harbinger Health Funding Rounds

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  • Series B

    $140,000,000 USD

  • Series A

    $50,000,000 USD

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