Senior Research Associate III, Early Discovery, CAR T Cell Therapy (24213-U-670-EDIS) - ArsenalBio

Job Title: Senior Research Associate III, Early Discovery, CAR T Cell Therapy (24213-U-670-EDIS)
Job Location: South San Francisco
Job Listing URL: https://jobs.lever.co/arsenalbio/83ee879f-6b10-410a-af4e-faadd5eb17b1
Job Description: WHO WE ARE
Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We are seeking a talented Senior Research Associate III, Early Discovery to work onsite based in our SOUTH SAN FRANCISCO office.

ArsenalBio’s mission and purpose is very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines with the goal to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across multi-scientific disciplines as well as clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.

We’re looking for a stellar Senior Research Associate to drive pioneering work in early discovery, and developing next-generation CAR T cell therapies for cancer. If you have a background in synthetic biology, immunology, or cellular/cancer biology and thrive on solving challenging problems with fresh ideas, this is the role for you! As a collaborative communicator, you’ll work across multiple disciplines with a talented, diverse team, pushing the limits of science in a fast-paced, cutting-edge environment. Bring your passion and expertise to help shape the future of cell therapy—join us to make a real impact in the fight against cancer!

WHAT YOU’LL DO
Generate engineered T cells to support in-vitro and in-vivo functional assays
Design and execute in vitro functional assays (co-culture, cytotoxicity, proliferation. etc) using genetically engineered T cells to support diverse projects
Run multicolor flow cytometry panels to assess phenotypic characteristics of tumor and/or immune cells
Get exposed to and support synthetic immunology construct design needs.
Support NGS efforts including library construction, sample QC, and executing sequencing runs
Summarize and synthesize data across experiments and present findings to colleagues, including diverse management teams
Work successfully in matrix organizations via the contribution of data, ideas, and presentations
Work with interdisciplinary teams including automation, NGS and compbio to establish and test novel logic-gated CAR T cell designs to enhance cell therapy

WHO YOU ARE
Master’s in immunology, cell biology, or related field with 2+ years of research experience, or Bachelor’s in the same fields with 4+ years of research experience.
Experience with general molecular biology techniques
Interest in working in a team setting and developing as a scientist both technically and conceptually
Aseptic culture technique and experience handling primary and transformed mammalian cells
Experience with multiparameter flow cytometry, ELISAs, and high throughput assays using luminescence, fluorescence or UV-visible absorbance
Data analysis experience using tools such as FlowJo and GraphPad Prism
Demonstrated ability to work well in a highly collaborative team environment
Willingness to accept other responsibilities outside of the initial job description
Strong organizational, record-keeping, and communication skills with the ability to quickly learn, stay productive, and deliver high-quality results.
Experience with automation or high throughput assays is a plus
Experience with data analysis using Python or R is a plus