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Senior Bioinformatician - Mantra Bio

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Job Title
Senior Bioinformatician
Job Location
South San Francisco, California, United States
Job Description

About Mantra Bio

At Mantra Bio we seek to create better medicines by developing next generation biologics based on our leading proprietary exosome engineering platform, REVEAL™. REVEAL™ integrates in silico computational biology and wet-lab automation to enable the rational design of engineered exosome therapeutics directed at a wide range of tissue and cellular targets. The foundation of our success is our truly interdisciplinary team who work collaboratively to accelerate therapeutic development. As a team, we value Self-Empowerment, Candor, Curiosity, and Collaboration and consider our human-centric culture to be our most important asset. We are proud to count 8VC, Viking, Samsung Securities, Illumina, Allen & Company and TenCent among our investors. Mantra Bio operates out of a newly constructed state-of-the-art facility in Oyster Point, South San Francisco.

Mantra Bio is seeking an experienced Bioinformatician to join our Data Science, Engineering, and Technology Team. You will be a key contributor to our exosome therapeutic programs that span both early R&D and preclinical IND efforts, collaborating across Mantra Bio with Process Scientists, Preclinical Scientists, Protein Scientists, and Data Scientists. The position requires broad technical experience developing robust data pipelines and deep knowledge of applied statistics in biology, medicine, or a closely related field. You will facilitate scientists’ use of internal and public data, provide guidance on experiment design, perform statistical analysis for in vitro and in vivo experiments, and train scientists on statistical tools and methods. Together with our team of Bioinformaticians, Data Scientists and Engineers, you will expand Mantra Bio’s data-centric approach to drive good, scalable science and accelerate progress toward our therapeutic mission.  



  • Collaborate with scientists on well-powered in vitro, in silico and in vivo experiment designs

  • Identify and perform proper statistical tests for analyses ranging from small animal studies to large screening experiments

  • Ingest publicly available datasets into our internal company architecture to power algorithm development by our Data Science team

  • Manage time and projects efficiently to support the analysis needs of multiple groups simultaneously

  • Create or verify trustworthy publication-level figures from critical in-house studies that will be presented at high-impact board and investor meetings

  • Act as a general mentor to Mantra Bio employees in areas of experimental design, quality control, statistical analysis, and graphical presentation of data


Your profile:

  • Master's degree in biostatistics, statistics or related field and 2+ years industry experience writing production level code required

  • Expertise in Python, including scipy and matplotlib required; experience with TensorFlow, Scikit-learn, and Pytorch preferred

  • Professional experience with SQL databases required; schema design and migration preferred

  • Strong understanding of statistical tests and exploratory statistics, including both metrics and visualization

  • Experience programmatically accessing public datasets such as UniProt, TCGA, Gene Ontology, or Gene Expression Omnibus

  • Demonstrated ability to collaborate with multiple stakeholder groups, including research scientists

  • Experience with Jupyter notebooks, dashboards, R, GCP, Kubernetes, TypeScript and React are nice to have

Annual Salary for this role - $120,000 to $145,000

Mantra Bio’s Culture:

At Mantra Bio, we value Self-Empowerment, Candor, Curiosity, and Collaboration. We take pride in being a human centric, collaborative work place that brings humble and wildly intelligent people together to build the next revolution in therapeutics. We believe that a great team makes a successful company and we trust each team member to do what’s best for the organization. We believe that a culture of feedback in an environment of empathy and respect is essential to cultivating curiosity and learning, while also leading to personal growth and the growth of our organization.  We love handing out Kudos, being creative, and celebrating our success together. We are committed to creating a diverse and inclusive environment and we are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.


  • Comprehensive health benefits package
  • 401k
  • Meaningful stock option grants
  • Flexible PTO and year-end shutdown
  • Generous Parental Leave program
  • Growth-oriented professional development opportunities
  • Team-building events
  • Fully stocked kitchen

Mantra Bio Headquarters Location

San Francisco, CA

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Mantra Bio Company Size

Between 20 - 50 employees

Mantra Bio Founded Year


Mantra Bio Total Amount Raised


Mantra Bio Funding Rounds

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  • Series A

    $9,000,000 USD

  • Series A

    $25,000,000 USD

Mantra Bio's Investors