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Scientist - Syntis Bio

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Job Title
Job Location
Boston, MA
Job Description

About Syntis Bio

Syntis Bio is a late-stage, preclinical company developing a new class of therapy. We create simple oral therapies and treatments targeting specific tissues through novel formulations. Our platform offers better outcomes through fewer doses, increased bioavailability, and higher efficacy to manage conditions affecting hundreds of millions of patients worldwide.

Syntis Bio is a growing company committed to building an inclusive workplace and developing people. Weโ€™re seeking candidates who are excited to shape our culture and contribute to organizational growth. 

We are located in the Seaport area in Boston, MA. Syntis Bio is pleased to offer comprehensive medical, dental and vision coverage options, flexible time off, and life and disability insurance. 

The Role:

Syntis Bio is seeking a Scientist to develop and optimize solid oral dosage formulations of small and large molecules utilizing proprietary platform technology. The Scientist will develop formulation-function relationships and optimize stable and scalable compositions. The ideal candidate will also work with key internal stakeholders and external CROs/CDMOs. The role will involve a clear presentation of technical data in a multi-disciplinary, matrixed environment. The position will require occasional travel to CRO/CDMOs for both execution and oversight of key experiments.


  • Build out composition space of solid oral dosage forms
  • Propose new formulation strategies for optimal performance, production, or stability
  • Develop a deep understanding of how formulation affects various aspects of function
  • Optimize or establish ex vivo tissue assays
  • Interpret, analyze, present, and properly record data
  • Support general lab upkeep (receiving, labeling, safely storing reagents, etc.)
  • Manage multiple projects and maintain expertise in formulation strategies for various targets
  • Apply broad drug delivery expertise to other projects and propose new formulation functions
  • Prepare documents and presentations that encompass project progression
  • Perform job-related duties as assigned

Ideal Skills:

  • PhD with 3+, MS with 5+, or BS with 10+ years working in the Biotech/Pharma industry with a degree in bioengineering, materials science, formulation sciences, chemical engineering, or physical organic chemistry
  • Comfortable with scientific ambiguity and has experience navigating it
  • Expertise working with drug formulations (liquids, suspensions, solids, and colloidal systems, etc.) for oral delivery, including those containing polymers and additional components known to improve in-vitro dissolution kinetics and increase in-vivo relative bioavailability
  • Experience with solid-state characterization, including, but not limited to DSC/TGA, PXRD, FTIR, SEM, BET, DVS
  • Skilled in collaborating or working with animal models (rodents, dogs, pigs)
  • Exposure to regulatory CMC requirements for early and late-stage clinical programs for medical devices, extended-release dosage forms as well as drug/device combination products
  • Strong record of deliberate mentorship or management of research technicians
  • Proven ability to lead the scientific direction of a project
  • Solid written and oral communication skills for technical and non-technical audiences
  • Conscientious team member with experience taking and giving constructive feedback

EEO Statement: Syntis Bio is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, age, sexual orientation, gender identity, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by applicable laws.

Recruitment & staffing agencies: Syntis Bio does not accept agency resumes unless contacted directly by internal Talent Acquisition. Please do not forward resumes to, Syntis Bio employees, or any other company location; Syntis Bio is not responsible for any fees related to unsolicited resumes.

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Syntis Bio Headquarters Location

Milton, MA

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Syntis Bio Company Size

Between 5 - 10 employees

Syntis Bio Founded Year


Syntis Bio Total Amount Raised


Syntis Bio Funding Rounds

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  • Series Unknown

    $15,372,179 USD